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Session Details

(9237-TC-PBM) Clinical Practice Guidelines from the AABB: Red Blood Cell Transfusion Thresholds and Storage

Director: Aaron Tobian, MD, PhD

Moderator: Aaron Tobian, MD, PhD

Faculty: Nancy Heddle, MSc, FCSMLS(D); Jeffrey Carson, MD; Aaron Tobian, MD, PhD

Intended Audience: Physicians, Scientists, Technologists, Nurses, Managers/Supervisors, CEOs/CFOs, Perfusionists

Teaching Level: Intermediate


  • Determine why AABB drafts clinical practice guidelines and how AABB applies GRADE methodology to draft guidelines.
  • Evaluate the medical evidence for the optimal target hemoglobin for red blood cell (RBC) transfusion of hospitalized hemodynamically stable adult patients and discuss AABB's recommendation.
  • Evaluate the medical evidence for the length of time RBCs should be stored prior to transfusion and discuss AABB's recommendation.

Event Description: Over 100 million units of blood are collected worldwide each year, yet the indication for RBC transfusion and RBC storage time remains uncertain. Large randomized clinical trials (RCTs) provide new evidence to guide RBC use. This fall the AABB published RBC transfusion guidelines. This session will provide the background for why AABB drafts clinical practice guidelines, describe the guideline development process, assess the randomized trial evidence and discuss the recommendations. 


Location: OCCC - W331 A