Immunohematology Boot Camp: MNS

Please note: AABB reserves the right to make updates to this program.

Live Program Date: Wednesday, January 18, 2017 – On-Demand Available
Master Program Number: 103 (see program format numbers below under Registration)

Educational Track: Technical/Clinical
Topic: Transfusion Medicine
Intended Audience: Physicians, Technologists, Managers/Supervisors, Laboratory Staff, Medical Directors, Students/Fellows, Residents, Hospital Blood Banks, Immunohematology Reference Labs (IRL’s), Facilities that perform molecular testing
Teaching Level: Intermediate

Director/Moderator: Eric A. Gehrie, MD, Assistant Professor of Pathology, Associate Director, Blood Bank, Johns Hopkins University, Baltimore, MD
Speakers: Laura Cooling, MD, MS, Associate Professor, Pathology, Associate Director, Transfusion Medicine, Medical Director, Immunohematology Reference Laboratory, Director, Cell Therapy Laboratory, University of Michigan Hospitals, Ann Arbor, MI; Rebecca Ross, MT (ASCP) SBB MA Ed, Assistant Chief of Blood Bank, Yale-New Haven Hospital, New Haven, CT

Learning Objectives

After participating in this educational activity, participants should be able to:

  • Understand the basic biochemistry and molecular biology of MNS system, including the generation of null phenotypes and MNS variants.
  • Name at least one role for MNS in red cell physiology and/or disease.
  • Differentiate IgM from IgG class anti-M, anti-N for various patient populations.
  • Determine when antigen negative products vs crossmatch compatible products should be provided.

Program Description

Antibodies to the MNS blood group antigens are frequently encountered in the blood bank. In this program, the speakers will discuss the biochemistry of the MNS system, the implications of MNS antigens for human disease, and the blood bank approach to positive antibody panels mediated by antibodies to MNS antigens.


   Program #
Single Viewer: On-Demand Register17EL-4035-103
Group Viewing: On-Demand Register17EL-8035-103

Speaker Biographies

Dr. Laura Cooling received her MD degree from the University of Iowa. She has been at the University of Michigan since 2000. At the University of Michigan, she serves as the associate director of the transfusion service, the medical director of the immunohematology reference laboratory, and director of the cell therapy laboratory. She is board certified by the American Board of Pathology in clinical pathology, with subspecialty certification in blood banking/transfusion medicine.

Rebecca Ross is a senior medical technologist with specialization in blood banking. She has decades of immunohematology experience, including 15 years at Yale-New Haven Hospital, where she is actively involved in the training of medical technology students and clinical pathology residents.