Immunohematology Boot Camp: Lewis, P and I Blood Group Antigens

Please note: AABB reserves the right to make updates to this program.

Live Program Date: Wednesday, August 23, 2017 - On-Demand Available

Master Program Number: 17EL-153 (see program format numbers below under Registration)

Educational Track: Technical/Clinical
Topic: Transfusion Medicine
Intended Audience: Laboratory Technologists, Blood Bank Specialists, Physicians
Teaching Level: Intermediate

Director/Moderator: Isabella Martin, MD, Transfusion Medicine Fellow, Dartmouth-Hitchcock Medical Center, Lebanon, NH
Speaker: Laura Cooling, MD, MSc, Associate Professor, Blood Bank; Associate Director, Blood Bank and Transfusion Services, University of Michigan, Ann Arbor, MI

Learning Objectives

After participating in this educational activity, participants should be able to:

  • Define the synthesis, structure and distribution of the Lewis, I and P antigens.
  • Highlight testing techniques and tips for detecting antibodies to this antigen group.
  • Describe the clinical significance of antibody formation to the Lewis, I and P antigens in transfusion practice.
  • Describe three disease associations.

Program Description

The Lewis, I and historical P system (now P1, GLOB, FORS) play a diverse role in tissue development, susceptibility to infectious disease, cancer and other diseases. Structurally-related to ABO, they can be a target of allo- and autoantibodies with varying degrees of clinical significance. This program will describe the synthesis, structure, distribution and clinical significance of the Lewis, I and P antigens as well as techniques and tips for testing.


   Program #
Single Viewer: On-Demand Register17EL-4035-153
Group Viewing: On-Demand Register17EL-8035-153

Speaker Biography

Dr. Laura Cooling is Associate Medical Director, Transfusion Medicine at the University of Michigan. She received her MD from the University of Iowa, followed by a residency in Clinical Pathology and fellowship in Transfusion Medicine at the University of Iowa Hospitals and Clinics. She was an Assistant Professor Pathology at the State University of New York at Syracuse for 3 years before joining the faculty at the University of Michigan. She is a past-president of the Michigan Association of Blood Banks and has served on several AABB committees including the Annual Meeting Education Program, Abstract Selection Program, Advisory Education Committee, Education Program Committee, Scientific Section Coordinating Committee, and Cellular Therapy Subsection. She has written several papers, reviews and book chapters in the area of glycosphingolipids, glycobiology, and immunohematology.