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Elementary Probability as Applied to Biological Relationship Determination

Please note: AABB reserves the right to make updates to this program.

Live Program Date: March 14, 2016 – On-Demand Version Available
Master Program # 164930 (see program format numbers below under Registration)

Educational Track: Technical/Clinical
Topic: Transfusion Medicine (Relationship Testing)
Intended Audience: Parentage Laboratory Managers and Technologists
Teaching Level: Basic/Intermediate

Moderator: Nikki Bass-Jeffrey (CQIA)ASQ, Accreditations Programs Coordinator, AABB, Bethesda, MD
Speaker: Charles M. Kelly, PhD, Director of IntelliGenetics, LLC, Atlanta, GA

Learning Objectives:

After participating in this educational activity, participants should be able to:

  • Review basic rules of probability, population and frequency.
  • Apply the basic probability rules to derive mathematical expressions for genotype likelihoods.
  • Calculate likelihood ratios for parentage given various scenarios of parental genotypes.
  • Calculate a probability of parentage from the likelihood ratio/paternity index.
  • Demonstrate the dependence of parentage probability on the weight of the non-genetic evidence in a legal proceeding.

Program Description

Participants will review basic probability principles using simple references to coin tosses and rolls of dice. Those principles will then be applied to biological inheritance and the calculation of parentage likelihood ratios. The effects of zygosity or the availability or unavailability of a parent on the final likelihoods will be made apparent.


   Program #
Single Viewer: On-Demand Register164930R
Group Viewing: On-Demand Register164930R-GRP