Immunohematology Boot Camp Series: HLA Antibodies – The Platelet Refractory Patient

Please note: AABB reserves the right to make updates to this program.

Wednesday, July 10, 2019
2:00 – 3:00 PM (ET) 7:00 – 8:00 PM (GMT)
Master Program Number: 19EL-450 (see program format numbers below under Registration)

Educational Track: Technical/Clinical
Topic: Transfusion Medicine
Intended Audience: Donor Recruitment Staff, Hospitals, Hospital Blood Banks, Laboratory Staff, Managers/Supervisors, Medical Directors, Nurses, Physicians, Resident/Fellow, Students (MD, MT, SBB), Technologists, Transfusion Safety Officers
Teaching Level: Intermediate to Advanced

Director/Moderator: Kerry L. O’Brien, MD, Medical Director Blood Bank, Beth Israel Deaconess Medical Center, Boston, MA
Speaker: J. Ryan Peña, MD, PhD, MS, D(ABHI), Medical Director HLA Laboratory, Beth Israel Deaconess Medical Center and Assistant Professor Pathology at Harvard Medical School, Boston, MA

Learning Objectives

After participating in this educational activity, participants should be able to:

  • Explain platelet refractoriness and etiologies.
  • Describe clinical and laboratory features of platelet refractoriness.
  • Describe transfusion support for platelet refractoriness.

Program Description

Platelet transfusion refractoriness is an increasing issue in heavily transfused patients such as patients with hematologic malignancies. The blood bank and HLA laboratory play an important role in assessing clinical refractoriness and helping clinicians determine whether there is an immune or non-immune etiology (or both). Dr. Peña will describe his institution’s approach to the platelet refractory patient.


   Program #
Single Viewer: Live Register19EL-450-2035
Single Viewer: On-Demand Register19EL-450-4035
Group Viewing: Live Register19EL-450-6035
Group Viewing: On-Demand Register19EL-450-8035
Group Viewing: Live & On-Demand Register19EL-450-9935

Continuing Education Credit

AABB estimates both the live and on-demand version of this eCast each to be eligible for 1 continuing education credits/contact hours for Physicians, California Nurse, California Lab Personnel, Florida Lab Personnel and General Participation credit. The final number of credit(s) and credit types awarded for this program (live or on-demand) will be determined by the program duration. For more information on each credit type please visit our Continuing Education Credits webpage.

Disclosures for the planners of this event can be found here. Disclosures for the program faculty are provided at the beginning of the program.

Speaker Biography

Dr. Ryan Peña received his PhD, MD from Baylor College of Medicine. He completed residency in Clinical Pathology and training in Histocompatibility and Immunogenetics at the Massachusetts General Hospital and fellowship training at the Harvard Medical School Joint Program in Transfusion Medicine. He currently serves as the Director of the HLA Laboratory at Beth Israel Deaconess Medical Center. His interests include studying the pathomechanisms of HLA antibodies and optimizing transfusion support of patients with HLA alloimmune platelet refractoriness.