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Donor Hemovigilance

The  Donor Hemovigilance is used to track and trend adverse events associated with blood donation with the goal of reducing their occurrence. Created through collaboration among the U.S. Department of Health and Human Services, the Armed Services Blood Program and the private sector — including AABB, America's Blood Centers, the American Red Cross, Blood Systems, Inc. and hospital blood collection centers — the program allows participating facilities to enter data into a web-based electronic data collection system, to analyze their facility’s donor data, to benchmark with aggregate donor hemovigilance data, and to identify trends.

Community-wide participation is crucial to the success of the Donor Hemovigilance Program. By collaborating with AABB, blood centers across the country can work together to help reduce adverse events associated with blood collection and improve overall donor safety.

 Benefits to Participating Centers

  • Use of internationally consistent definitions for adverse reactions associated with blood donation
  • Use of the DonorHART™ (Donor Hemovigilance Analysis and Reporting Tool)
  • Benchmark internally, with other blood centers, and against national averages
  • Access to in-depth analyses by qualified experts for the purpose of recommending nationwide donor health and safety enhancements
  • Mitigate risk
  • Gain a better understanding of the rare, serious adverse donor reactions through aggregating data nationally with other blood collectors


To enroll in the Donor Hemovigilance Program, please complete the following steps:

Once those steps are completed, AABB will assign your facility a log-in and password to the DonorHART™ training environment. Once your blood collection center completes the AABB Donor Hemovigilance Program Participation Agreement, blood center staff can enter the live DonorHART™ environment and begin participating by adding data and generating reports and graphs.


Blood centers participating in the AABB Donor Hemovigilance Program enter reports of adverse donor reactions and donor demographic denominator data manually or upload .csv files to populate the database. Once populated, DonorHART™ allows users to generate tables, reports and graphics to show granular detail about adverse reactions, donor demographics, and pertinent reaction rates. System-level reports are available through the software.

 Annual Participation Fee

The annual participation fee for the AABB Donor Hemovigilance Program, including access to DonorHART™, is modeled with tiered pricing that is aligned with a facility’s number of blood collection procedures. The table below reflects the annual participation fee pricing structure.

Annual Fee TierNumber of Manual and Apheresis Blood Collection Procedures per YearAnnual Participation Fee
Tier 1< 10,000 collection procedures$400
Tier 210,000 to 20,000 collection procedures$600
Tier 320,001 to 100,000 collection procedures$0.03 per collection procedure
Tier 4100,001 to 500,000 collection procedures$0.02 per collection procedure
Tier 5> 500,000 collection procedures$0.015 collection procedure

For example, a facility with 80,000 collection procedures annually will pay an annual Tier 3 participation fee of $2,400 (80,000 x 0.03/collection = $2,400).

Questions? Contact or +1.301.215.6588.