When a hospital participates in the CDC's NHSN Hemovigilance Module, it collects data about adverse reactions and incidents associated with transfusion in their facilities, then classifies and reports them into the system according to protocol on a regular (at least monthly) basis. Data can be analyzed locally by the hospital in real time.

In addition, AABB recommends that hospitals join AABB's Transfusion Safety Group to add their data into the analyses, which will result in development of interventions and practice improvements. Benchmarking reports and additional feedback will be provided to hospitals that participate with AABB.