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Serology of Warm Autoimmune Hemolytic Anemia – Case Studies

Please note: AABB reserves the right to make updates to this program.

Live Program: Wednesday, September 13, 2017 - On-Demand Available

Master Program Number: 17EL-156 (see program format numbers below under Registration)

Educational Track: Technical/Clinical
Topic: Transfusion Medicine
Intended Audience: Physicians, Scientists, Technologists, Managers/Supervisors, Laboratory staff, Medical Directors, Students, Fellows, Residents, Hospital Blood Banks, Immunohematology Reference Labs (IRL’s)
Teaching Level: Intermediate

Director/Moderator: NurJehan Quraishy, MD, Assistant Medical Director Transfusion Medicine, Assistant Professor, Lerner College of Medicine, Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH
Speakers: Patricia Arndt, MS, MT(ASCP)SBB, Lead Technologist, Special Immunohematology Lab, American Red Cross, Southern California Blood Services Region, Pomona, CA; Regina Leger, MSQA, MT(ASCP)SBB, CMQ/OE(ASQ), Lead Technologist, Special Immunohematology Lab, American Red Cross, Southern California Blood Services Region, Pomona, CA

Learning Objectives

After participating in this educational activity, participants should be able to:

  • Discuss adsorption techniques using autologous and allogeneic RBCs for the detection of alloantibodies underlying warm autoantibodies.
  • List three reasons for a negative DAT in a patient with warm autoimmune hemolytic anemia.
  • List five serological characteristics seen in patients with IgM warm autoimmune hemolytic anemia.

Program Description

Through a series of case studies, the speakers will discuss the diagnosis of warm autoimmune hemolytic anemia (AIHA), including the required clinical information, and the essential laboratory tests necessary to help identify the type of autoantibody. The topics covered will include 1) the use of adsorption techniques for detection of underlying alloantibodies, 2) DAT negative warm AIHA, and 3) the difficult-to-diagnose IgM warm AIHA, contrasting it with cold agglutinin disease and mixed-type AIHA.

Registration

   Program #
Single Viewer: On-Demand Register17EL-4035-156
Group Viewing: On-Demand Register17EL-8035-156

Speaker Biographies

Patricia Arndt, MS, MT(ASCP)SBB is currently a Lead Technologist in the Special Immunohematology Laboratory at the American Red Cross Blood Services, Southern California Region. For a little over three decades, she had been a Research Associate in the late Dr. George Garratty’s Research Lab at that same location. She is also a lecturer for the ARCBS, SCR’s Transfusion Medicine Lecture Series and a mentor for their Specialist in Blood Bank Technology & Transfusion Medicine Program.

Regina Leger, MSQA, MT(ASCP)SBB, CMQ/OE(ASQ) is a Lead Technologist in the Special Immunohematology Lab at the American Red Cross Blood Services, Southern California Region. Gina was a Research Associate in Dr. George Garratty’s Research Lab for over 20 years and was a Reference Laboratory Specialist prior to that. She lectures for the region's Transfusion Medicine Lecture Series and is the Program Director for the Specialist in Blood Bank Technology & Transfusion Medicine Program.