Immunohematology Boot Camp Series: Monoclonal Antibody Therapy Interference and How to Avoid It

Please note: AABB reserves the right to make updates to this program.

Live Program: Wednesday, February 27, 2019 - On-Demand Available

Master Program Number: 19EL-402 (see program format numbers below under Registration)

Educational Track: Technical/Clinical
Topic: Transfusion Medicine
Intended Audience: Directors, Facilities that perform molecular testing, Hospitals, Hospital Blood Banks, Immunohematology Reference Labs (IRL’s), Laboratory Staff, Managers/Supervisors, Medical Directors, Physicians, Research Scientist, Resident/Fellow, Scientists, Students (MD, MT, SBB), Technologists, Transfusion Safety Officers
Teaching Level: Basic to Intermediate

Director/Moderator: Lisa M. Shave, MS, MLS(ASCP)CMSBBCM, Medical Laboratory Scientist, Pennsylvania Hospital, Philadelphia, PA, Medical Laboratory Technology Program Coordinator, Mercer County Community College, West Windsor, NJ
Speaker: Susan T. Johnson, MSTM, MT(ASCP)SBB, Director, Clinical Education, Director at Versiti Wisconsin’s Specialist in Blood Banking (SBB) Program and Transfusion Medicine Program at Marquette University, Versiti, Inc., Milwaukee, WI

Learning Objectives

After participating in this educational activity, participants should be able to:

  • List more commonly encountered monoclonal antibody therapy that can affect pretransfusion testing.
  • Describe how these monoclonal antibodies cause interference in ABO, Rh typing, antibody detection and identification.
  • Discuss strategies to avoid or work around monoclonal antibody therapy interference.

Program Description

Pretransfusion testing can become complicated when patients receive monoclonal antibody therapy for multiple myeloma and other cancers. Strategies are being developed to avoid reactivity in antibody detection and identification. A review of these approaches will be discussed along with advantages and limitations of each.


   Program #
Single Viewer: On-Demand Register19EL-402-4035
Group Viewing: On-Demand Register19EL-402-80**

Continuing Education Credit

AABB designates both the live and on-demand version of this eCast each to be eligible for 1.0 continuing education credits/contact hours for Physicians, California Nurse, California Lab Personnel, Florida Lab Personnel and General Participation credit. The number and type of credits awarded for this program (both live and on-demand) was determined by the program duration. For more information on each credit type please visit our Continuing Education Credits webpage.

Disclosures for the planners of this event can be found here. Disclosures for the program faculty are provided at the beginning of the program.

Speaker Biography

Sue Johnson is the Director of Clinical Education at Versiti Wisconsin, as well as the director of the Specialist in Blood Banking Program. She has taught laboratory science students for over 25 years and is one of the most respected voices in Transfusion Medicine education. She is also the Director of the Transfusion Medicine Program at Marquette University and Associate Director of the Indian Immunohematology Program. She has extensive experience as a teacher, author, and international lecturer.