Diagnosing Adverse Transfusion Reactions: Learning from Case Studies and Blood Center Workups

Please note: AABB reserves the right to make updates to this program.

Live Program Date: Thursday, August 22, 2019 - On-Demand Available

Master Program Number: 19EL-466 (see program format numbers below under Registration)

Educational Track: Technical/Clinical
Topic: Transfusion Medicine (Hemovigilance)
Intended Audience: Hospitals, Hospital Blood Banks, Laboratory Staff, Managers/Supervisors, Medical Directors, Nurses, Physicians, Research Scientists, Residents/Fellows, Scientists, Students (MD, MT, SBB)
Teaching Level: Basic to Intermediate

Director/Moderator: Chester Andrzejewski, MD, PhD, Medical Director, System Transfusion Medicine, Baystate Medical Center, Springfield, MA
Speakers: Nancy L. Van Buren, MD, Medical Director, Innovative Blood Resources, Saint Paul, MN; Stephanie Bates, MD, Assistant Professor, Medical Director of Transfusion Service, Coagulation Laboratory, HPC Processing Laboratory, University of Oklahoma Medical Center, Oklahoma City, OK

Learning Objectives

After participating in this educational activity, participants should be able to:

  • Apply CDC National Healthcare Safety Network (NHSN) case definition criteria to identify adverse transfusion reactions through presented cases studies.
  • Identify adverse transfusion reactions that need to be reported to blood centers for further investigation.
  • Identify scenarios where donors might get deferred as a result of adverse transfusion reaction to patients.

Program Description

Diagnosing adverse transfusion reactions (ATR) is often challenging and complicated. Certain adverse reactions get reported to blood centers for further investigation. This program will present case studies that will help the audience understand the clinical signs and symptoms, lab works, vitals and investigations to diagnose and classify ATRs. The audience will also learn about workups that blood centers conduct to provide final diagnosis for certain ATRs.


   Program #
Single Viewer: On-Demand Register19EL-466-4032
Group Viewing: On-Demand Register19EL-466-8032

Continuing Education Credit

AABB designates both the live and on-demand version of this eCast each eligible for 1 continuing education credits/contact hours for Physicians, General Participation, California Nurse, California Lab Personnel and Florida Lab Personnel. The number and type of credits awarded for this program (both live and on-demand) was determined by the program duration. For more information on each credit type please visit our Continuing Education Credits webpage.

Disclosures for the planners of this event can be found here. Disclosures for the program faculty are provided at the beginning of the program.

Speaker Biographies

Dr. Stephanie Bates received her MD degree from The University of Texas Health Science Center Houston and completed her Fellowship in Transfusion Medicine/Blood Banking at Baylor College of Medicine. Dr. Bates enjoyed appointments as Associate Medical Director of the Transfusion Service and Donor Center at St. Luke's Episcopal Hospital in the Texas Medical Center. Currently, Dr. Bates is the Medical Director of Transfusion Medicine, Hematopoietic Progenitor Cell Processing Laboratory, and Coagulation Laboratory at OU Medicine in Oklahoma City.

Dr. Nancy Van Buren is a member of the AABB Donor Hemovigilance Working Group and assisted with the development of standardized donor reaction definitions on the Donor Reaction Severity subcommittee. She is Associate Medical Director and CLIA Laboratory Director for Innovative Blood Resources (IBR, including Memorial Blood Centers and Nebraska Community Blood Blank), which is part of the New York Blood Center enterprises. Prior to joining IBR, she had over 25 years of experience as a hospital pathologist and transfusion services medical director in Tennessee and Minnesota, including 15 years managing a hospital-based blood donor program. Through her work at the blood center, she developed an interest in collections quality and donor safety. She is currently the co-medical director of Transfusion Services at Hennepin County Medical Center, as well as Children’s Hospitals and Clinics of Minnesota in Minneapolis and St. Paul. She is board certified in anatomic and clinical pathology with subspecialty certification in blood banking and transfusion medicine. She received a BA in Biology from St. Olaf College, her MD from the University of Minnesota, and pathology residency training in Minnesota, including a fellowship in Blood Banking and Transfusion Medicine at the University of Minnesota.