Donor Adverse Reactions Severity Grading: Validating the Proposed Grading Tool

Please note: AABB reserves the right to make updates to this program.

Live Program Date: Thursday, September 5, 2019 - On-Demand Available

Master Program Number: 19EL-470 (see program format numbers below under Registration)

  • Educational Track: Quality Education
  • Topic: Hemovigilance
  • Intended Audience: CEOs, Directors, Hospital Blood Banks, Laboratory Staff, Managers/Supervisors, Medical Directors, Nurses, Physicians, Research Scientists, Residents/Fellows, Scientists, Students (MD, MT, SBB)
  • Teaching Level: Basic, Intermediate
  • Moderator: James R. Stubbs, MD, Medical Director, Mayo Clinic, Rochester, MN
    Speakers: Mary J. Townsend, MD, Medical Director, Vitalant, Scottsdale, AZ; Nancy L. Van Buren, MD, Medical Director, Innovative Blood Resources, Saint Paul, MN

  • Learning Objectives

    After participating in this educational activity, participants should be able to:

    • Define categories of severity.
    • Describe the development and application of the Severity Assessment Tool for reaction classification.
    • Discuss preliminary validation study results.
    • Apply severity grading to various clinical scenarios through presented cases studies.

    Program Description

    A consistent assessment of the severity of donor adverse reactions is critical for understanding their impact. It will also help your donor center engage in comparative trend analysis with other blood collections, both locally and globally. This program will include a review of the proposed severity grading of blood donor adverse event tools developed by the AABB Donor Hemovigilance Working Group. Preliminary results from the international validation study will be presented along with several case studies to help the audience evaluate the clinical validity and applicability of the severity grading.


    Program #
    Single Viewer: On-Demand Register 19EL-470-4032
    Group Viewing: On-Demand Register 19EL-470-8032

    Continuing Education Credit

    AABB designates both the live and on-demand version of this eCast each eligible for 1 continuing education credits/contact hours for Physicians, General Participation, California Nurse, California Lab Personnel and Florida Lab Personnel. The number and type of credits awarded for this program (both live and on-demand) was determined by the program duration. For more information on each credit type please visit our Continuing Education Credits webpage.

    Disclosures for the planners of this event can be found here. Disclosures for the program faculty are provided at the beginning of the program.

    Speaker Biographies

    Dr. Townsend serves as the Senior Medical Director, National Office at Vitalant in Scottsdale, AZ. Born in Nocona, Texas, Mary earned her bachelor’s degree in Chemistry and her master’s degree in Physical Chemistry prior to attending medical school at UT Southwestern in Dallas, TX. She trained in Obstetrics and Gynecology at the University of Pennsylvania and completed her residency in Clinical Pathology at the Medical College of Pennsylvania. Mary has spent her career focusing on the care and feeding of donors, for whom she has an abiding passion. She was an inaugural member of the AABB Task Force to redesign the uniform donor questionnaire, serving as its second chair. She chaired both the America’s Blood Centers’ Scientific, Medical, Technical and Quality committee and the ABC Donor Adverse Event committee. She has been a member of the AABB Donor Biovigilance Working Group since its inception and was one of three centers to pilot the DonorHART Biovigilance system. She has been an editor of Notify Library since 2015, focusing on donor adverse events and infectious events in recipients.

    Dr. Nancy Van Buren is a member of the AABB Donor Hemovigilance Working Group and assisted with the development of standardized donor reaction definitions on the Donor Reaction Severity subcommittee. She is Associate Medical Director and CLIA Laboratory Director for Innovative Blood Resources (IBR, including Memorial Blood Centers and Nebraska Community Blood Blank), which is part of the New York Blood Center enterprises. Prior to joining IBR, she had over 25 years of experience as a hospital pathologist and transfusion services medical director in Tennessee and Minnesota, including 15 years managing a hospital-based blood donor program. Through her work at the blood center, she developed an interest in collections quality and donor safety. She is currently the co-medical director of Transfusion Services at Hennepin County Medical Center, as well as Children’s Hospitals and Clinics of Minnesota in Minneapolis and St. Paul. She is board certified in anatomic and clinical pathology with subspecialty certification in blood banking and transfusion medicine. She received a BA in Biology from St. Olaf College, her MD from the University of Minnesota, and pathology residency training in Minnesota, including a fellowship in Blood Banking and Transfusion Medicine at the University of Minnesota.