Immunohematology Boot Camp: RH Variants (22EL-732)

Please note: AABB reserves the right to make updates to this program.

Live Program Date: Wednesday, May 11, 2022 - On-Demand Available

Program Number: 22EL-732

  • Educational Track: Technical/Clinical
  • Topic: Patient Transfusion
  • Intended Audience: Facilities that perform molecular testing, Hospital Blood Banks, Immunohematology Reference Labs (IRL’s), Laboratory Staff, Managers/Supervisors, Medical Directors, Residents/Fellows
  • Teaching Level: Intermediate
  • Director/Moderator: Lynsi Rahorst, MHPE, MT(ASCP)SBBCM, Manager, Education & Training IRL/Genomics, New York Blood Center Enterprises, Kansas City, MO

    • Sunitha Vege, MS, Technical Director, Genomics Laboratory, New York Blood Center, Long Island City, NY
    • Gorka Ochoa-Garay, PhD, Director of Bioinformatics and Assay Development, New York Blood Center, Long Island City, NY
  • Program Description

    Over the past decades, the number and our understanding of altered RH alleles has increased significantly. While serologic methods were initially used to describe altered Rh phenotypes, molecular methods have provided an explanation for the altered expression of Rh antigens. In addition, they have uncovered over 1,000 RH alleles in various human populations. Understanding the genetic mechanisms that lead to altered RH alleles and the currently available detection methods can improve selection of blood for transfusion.

    In this program, the faculty will review the transfusion challenges presented by patients with altered RH alleles and discuss case studies that exemplify the strengths and limitations of current testing strategies.

    Learning Objectives

    After participating in this educational activity, participants should be able to:

    • Describe the challenges associated with the transfusion of patients with altered RH alleles.
    • Identify the common genetic mechanisms that lead to altered RH alleles.
    • Discuss the molecular methods utilized to identify RH alleles, including their strengths and limitations.
    • Discuss case studies involving complex RH alleles and make transfusion recommendations.


    Please note: If you registered for the live eCast you do not need to register for the on-demand eCast (access to the on-demand eCast was included with the live eCast registration).

    Single Viewer Register
    Group Viewing Register

    Continuing Education Credit

    This activity is eligible for one (1) continuing education credit/contact hour for Physicians, Nurses (including California-based nursing professionals through CBRN), California Lab Personnel, Florida Lab Personnel and General Participation credit. AABB reserves the right to reduce or increase the number of credits granted based on the final activity duration. For more information on each credit type please visit our Continuing Education Credits webpage.

    There is no financial support for this activity.

    Jointly Accredited Provider

    In support of improving patient care, this activity has been planned and implemented by the Association for the Advancement of Blood & Biotherapies (AABB) and CME Outfitters, LLC. CME Outfitters LLC. is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

    Physicians (ACCME): CME Outfitters, LLC, designates this live/enduring activity for a maximum of one (1) AMA PRA Category 1 CreditTM. CME Outfitters, LLC, designates this enduring activity for a maximum of one (1) AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Claiming Credit
    Live Activity - Upon completion of the live activity, you will receive instructions to complete your evaluation, which is necessary to claim credit and receive your certificate of attendance/completion (credit must be claimed by the date provided in the instructions). The evaluation can be found by logging into the AABB Education Platform.

    Enduring Activity - Once the enduring (on-demand) program is available, you will receive instructions to access the AABB Education Platform. Upon completion of viewing the enduring activity, you will need to complete the evaluation and post quiz, which is necessary to claim credit and receive your certificate of completion (credit must be claimed by the date provided in the AABB Education Platform).

    Program & Credit Expiration Dates:

    • Live Activity Program Date: May 11, 2022; Credit Expiration Date: June 11, 2022
    • Enduring Activity Program Dates: May 11, 2022 – May 10, 2025; Credit Expiration Date: May 10, 2025

    Disclosure Declaration

    It is the policy of CME Outfitters, LLC, and the Association for the Advancement of Blood & Biotherapies to ensure independence, balance, objectivity, and scientific rigor and integrity in all of their CE activities. Faculty must disclose to the participants any relationships with commercial companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. CME Outfitters, LLC, has evaluated, identified, and mitigated any potential conflicts of interest through a rigorous content validation procedure, use of evidence-based data/research, and a multidisciplinary peer review process. The following information is for participant information only. It is not assumed that the presence of such relationships will have a negative impact on the presentations.

    Disclosures for the planners of this event can be found here. Disclosures for the program faculty, peer reviewers, and CME Outfitters, LLC. personnel are provided at the beginning of the program.

    Speaker Biographies

    Gorka Ochoa-GarayDr. Ochoa obtained his M.D. at the University of the Basque Country in Bilbao, Spain, and his Ph.D. in Microbiology & Immunology from the University of Southern California. He completed his post-doctoral training at the NIAID in Rockville, MD and at the Gladstone Institute of Immunology in San Francisco. Dr. Ochoa worked as a Research Associate at the Johns Hopkins University in Baltimore, as Research Manager at Progenika Biopharma in Bilbao, Spain, as Technical Supervisor at Progenika in Medford, MA and as Lab Director at Grifols in San Marcos, TX. Currently, he is Director of Bioinformatics & Assay Development at New York Blood Center in Long Island City, NY.

    Sunitha Vege Sunitha Vege is the Technical Director of the Genomics Laboratory at the New York Blood Center. She received her Master’s in Ecology and Evolutionary Biology and more recently, in Bioinformatics. She has been working in the blood group genotyping field for over 15 years with particular interest in the RH system and its genetic diversity. She has presented at state and national meetings and has co-authored numerous publications in the area.