Standards for Molecular Testing for Red Cell, Platelet, and Neutrophil Antigens, 8th edition – Print

The 8th edition of Standards for Molecular Testing for Red Cell, Platelet, and Neutrophil Antigens (MT Standards) contains requirements for facilities using molecular methods to predict blood group antigens on red cells, platelets, and neutrophils, as well as quality system requirements, operational standards, and a detailed list of inventory resources necessary for the identification of targeted nucleotides that encode these antigens.

The MT Standards addresses operational aspects such as test methods including Restriction Fragment Length Polymorphism Testing, DNA Testing for Nucleotide Sequence Determination or Single Nucleotide Polymorphism (SNP) Analysis, and DNA Array. The guiding principle of this document is to be consistent with available scientific information while focusing on patient advocacy and optimal care for donors. These MT Standards represent the minimum requirements under which a laboratory specializing in molecular testing should operate.

Significant changes to the 8th edition

• Addition to ensure that clear communication exists between AABB and all accredited laboratories in cases where an event has occurred that has impacted their accreditation status.
• Reference Standard 2.2A has been expanded to include three new blood groups that have been added to the GenBank Database.
• Addition to ensure that all laboratories monitor their critical technology infrastructure and that they function as expected. There must be defined checks to monitor that technology is working as intended and expected.
• Addition requiring that facilities performing fetal cell-free DNA testing conduct additional validation studies before they implement.
• Laboratories must have a plan to participate in the publication of novel alleles.

Effective date: January 1, 2027

PRINT EDITION: AABB, 2026, 116 pages, ISBN 978-1-56395-565-5

Product Code: 263115
Member Price: $153
Nonmember Price: $175

Item Details:

View Table of Contents (pdf)

View Preface (pdf)

View Sample Pages (pdf)