Immunohematology Boot Camp: Duffy (22EL-772)

Please note: AABB reserves the right to make updates to this program.

Wednesday, September 14, 2022
2:00 – 3:00 PM Eastern Time
Program Number: 22EL-772

  • Educational Track: Technical/Clinical
  • Topic: Patient Transfusion
  • Intended Audience: Immunohematology Reference Labs (IRL’s), Laboratory Staff, Managers/Supervisors, Medical Directors, Physicians, Residents/Fellows, Students (MD, MT, SBB), Technologists
  • Teaching Level: Basic, Intermediate
  • Director/Moderator: Sheri Goertzen, MT(ASCP)BB, CLS(CA), CQA(ASQ), Supervisor, Transfusion Service, Valley Children’s Healthcare, Madera, CA

    • Jayanna Slayten MS, MT(ASCP) SBBcm, Supervisor, IUH Blood Bank, Indiana University Health, Indianapolis, IN; Adjunct Faculty, University of Texas Medical Branch, Galveston, TX
  • Program Description

    This program will describe the structure, distribution, and clinical significance of the Duffy Blood Group System. Antibodies to Duffy antigens are usually clinically significant and have been reported to cause hemolytic disease of the fetus and newborn. The FY glycoprotein, atypical chemokine receptor 1 ACKR1 will be explored and altered expressions of the alleles will be defined. Case studies will demonstrate how antibodies in this blood group may be detected in the blood bank.

    Learning Objectives

    After participating in this educational activity, participants should be able to:

    • Describe the clinical significance of antibody formation to the Duffy antigens in clinical practice.
    • Explain the significance of the GATA promoter region mutation as it relates to individuals who appear Fy(a-b-).
    • Highlight the role of the Duffy glycoprotein in malarial infections.
    • Explore the functional aspects of the FY Glycoprotein, ACKR1.
    • Apply the known serologic characteristics of the antibodies in the Duffy system to resolve complex serologic case studies.


    Registration includes access to both the live and on-demand version of this eCast.

    If you are a facility interested in participating in this eCast, simply complete the Group Viewing registration form and AABB will provide detailed instructions to share with your team approximately one week prior to the live program (each team member to register for the program utilizing a promocode). For single viewers, simply click on the Register button below to register.

    Please note: registration for the live eCast will close 1 hour prior to the eCast start time. If you register after this time you will receive access to the on-demand eCast when it is available.

    Single Viewer Register
    Group Viewing Register

    Continuing Education Credit

    AABB estimates both the live and on-demand version of this eCast each to be eligible for 1 continuing education credits/contact hours for Physicians, California Nurse, California Lab Personnel, Florida Lab Personnel and General Participation credit. The final number of credit(s) and credit types awarded for this program (live or on-demand) will be determined by the program duration. For more information on each credit type please visit our Continuing Education Credits webpage.

    Disclosures for the planners of this event can be found here. Disclosures for the program faculty are provided at the beginning of the program.

    Speaker Biography

    Jayanna Slayten is from Indianapolis, Indiana. She is a Supervisor of the Blood Bank at Indiana University Health responsible for Transfusion Service leadership at Riley Hospital for Children, University Hospital and Methodist Hospital. She attended Georgetown College and the University of Kentucky for her undergraduate work. Jay received her Master’s in Blood Transfusion Medicine and Specialist in Blood Bank (SBB) in 1998 from the University of Cincinnati and the Hoxworth Blood Center. Besides a love for red cell serology, Jay enjoys blood bank teaching as she is an adjunct faculty member of the SBB Program at the University of Texas Medical Branch, participates in many AABB committees and AABB Annual Meeting presentations, and often presents for the Indiana State Association of Blood Banks Spring Workshop and Annual Meetings. Jay is the wife to Phillip and mother to growing teenage boys - Ben, Chris, and Jon.