Immunohematology Boot Camp: HLA Antibodies – The Platelet Refractory Patient (23EL-805)

Please note: AABB reserves the right to make updates to this program.

Live Program Date: Wednesday, February 8, 2023 - On-Demand Available

Program Number: 23EL-805

  • Educational Track: Technical/Clinical
  • Topics: Blood Donation & Collection, Patient Transfusion
  • Intended Audience: Hospital Blood Banks, Immunohematology Reference Labs (IRL’s), Laboratory Staff, Physicians, Residents/Fellows, Students (MD, MT, SBB), Technologists
  • Teaching Level: Basic, Intermediate
  • Director/Moderator: Danielle Mullins, MSTM, MLS(ASCP)CMSBBCM, Manager, Quality Assurance, Immunohematology Reference Laboratory, Versiti Illinois, Aurora, IL

    • Jennifer Herring, BS, SBB(ASCP)CM, CHT(ABHI), Team Lead Laboratory Scientist– IRL/HLA, Versiti Michigan, Grand Rapids, MI
  • Program Description

    This program is designed to define platelet refractoriness, detail common laboratory values associated with refractoriness, and recognize these in the context of a patient case. In addition, distinguish platelet refractoriness from other common platelet issues. This program will be a lecture-based presentation interlaced with case studies to demonstrate relevant laboratory and clinical findings.

    Learning Objectives

    After participating in this educational activity, participants should be able to:

    • Define platelet refractoriness.
    • Identify causes of platelet refractoriness, recognize the signs within the context of a patient case presentation, and differentiate from other common platelet issues.
    • List the test results that indicate a patient is in a refractory state and calculate the corrected platelet count.
    • Define the calculated PRA, recognize the clinical significance, and discuss the implications for transfusion.


    Please note: if you registered for the live eCast you do not need to register for the on-demand eCast (access to the on-demand eCast was included with the live eCast registration).

    Single Viewer Register
    Group Viewing Register

    Continuing Education Credit

    This activity is eligible for one (1) continuing education credit/contact hour for Physicians, Nurses (including California-based nursing professionals through CBRN), California Lab Personnel, Florida Lab Personnel and General Participation credit. AABB reserves the right to reduce or increase the number of credits granted based on the final activity duration. For more information on each credit type please visit our Continuing Education Credits webpage.

    There is no financial support for this activity.

    Jointly Accredited Provider

    In support of improving patient care, this activity has been planned and implemented by the Association for the Advancement of Blood & Biotherapies (AABB) and CME Outfitters, LLC. CME Outfitters LLC. is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

    Physicians (ACCME): CME Outfitters, LLC, designates this live activity for a maximum of one (1) AMA PRA Category 1 CreditTM. CME Outfitters, LLC, designates this enduring activity for a maximum of one (1) AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Claiming Credit
    Live Activity - Upon completion of the live activity, you will receive instructions to complete your evaluation, which is necessary to claim credit and receive your certificate of attendance/completion (credit must be claimed by the date provided in the instructions). The evaluation can be found by logging into the AABB Education Platform.

    Enduring Activity - Once the enduring (on-demand) program is available, you will receive instructions to access the AABB Education Platform. Upon completion of viewing the enduring activity, you will need to complete the evaluation, which is necessary to claim credit and receive your certificate of completion (credit must be claimed by the date provided in the AABB Education Platform).

    Program & Credit Expiration Dates:

    • Live Activity Program Date: February 8, 2023; Credit Expiration Date: March 8, 2023
    • Enduring Activity Program Dates: February 8, 2023 – February 7, 2026; Credit Expiration Date: February 7, 2026

    Disclosure Declaration

    It is the policy of CME Outfitters, LLC, and the Association for the Advancement of Blood & Biotherapies to ensure independence, balance, objectivity, and scientific rigor and integrity in all of their CE activities. Faculty must disclose to the participants any relationships with commercial companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. CME Outfitters, LLC, has evaluated, identified, and mitigated any potential conflicts of interest through a rigorous content validation procedure, use of evidence-based data/research, and a multidisciplinary peer review process. The following information is for participant information only. It is not assumed that the presence of such relationships will have a negative impact on the presentations.

    Disclosures for the planners of this event can be found here. Disclosures for the program faculty, peer reviewers, and CME Outfitters, LLC. personnel are provided at the beginning of the program.

    Faculty Biographies

    Jennifer Herring is the Team Lead of the Versiti Michigan IRL and HLA laboratories. She started her career in a blood center, transitioning into the IRL in 2005. She stumbled into the HLA world in 2013. Since then, she has been involved in both HLA and IRL obtaining her Certified Histocompatibility Technologist (CHT) certification in 2015 and her Specialist in Blood Banking (SBB) certification in 2020.

    Danielle Mullins is the Quality Assurance Manager of the Immunohematology Reference Laboratory at Versiti Illinois. She obtained her SBB certification in 2018 and Masters of Science in Transfusion Medicine from Marquette University in 2020. Danielle has a passion for education and teaching the next generation of laboratory scientists.