Genotype Matching and Best Recommendations for Transfusion (23EL-827)

Please note: AABB reserves the right to make updates to this program.

Live Program Date: Wednesday, April 26, 2023 - On-Demand Available

Program Number: 23EL-827

  • Educational Track: Technical/Clinical
  • Topics: Blood Donation & Collection, Patient Transfusion
  • Intended Audience: Directors, Hospital Blood Banks, Hospitals, Immunohematology Reference Labs (IRL’s), Laboratory Staff, Managers/Supervisors, Medical Directors, Physicians, Residents/Fellows, Scientists, Students (MD, MT, SBB), Technologists, Transfusion Safety Officers
  • Teaching Level: Intermediate
  • Director/Moderator: David Unold, MD, Health Sciences Associate Clinical Professor, UC Davis, Sacramento, CA

    • Sunitha Vege, MS, Technical Director, Genomics Laboratory, New York Blood Center, New York, NY
  • Program Description

    Red cell genotyping is a powerful tool in transfusion medicine. The DNA testing can be used to obtain an extended predicted antigen profile on patients, identify those with altered alleles, and aid in resolution of difficult antibody workups. Genotyping of donors can improve the availability and selection of suitable units for transfusion. This program will explore the application of patient red cell genotype testing and current and future donor genotyping strategies. These approaches will also be illustrated through case studies.

    Learning Objectives

    After participating in this educational activity, participants should be able to:

    • List the common indications for performing red cell genotyping in transfusion medicine.
    • Discuss the role of genotype matching in reducing alloimmunization, especially in patients receiving chronic transfusions.
    • Review case studies of genotype testing and matching of patients with multiple antibodies and altered alleles.


    Please note: if you registered for the live eCast you do not need to register for the on-demand eCast (access to the on-demand eCast was included with the live eCast registration).

    Single Viewer Register
    Group Viewing Register

    Continuing Education Credit

    This activity is eligible for one (1) continuing education credit/contact hour for Physicians, Nurses (including California-based nursing professionals through CBRN), California Lab Personnel, Florida Lab Personnel and General Participation credit. AABB reserves the right to reduce or increase the number of credits granted based on the final activity duration. For more information on each credit type please visit our Continuing Education Credits webpage.

    There is no financial support for this activity.

    Jointly Accredited Provider

    In support of improving patient care, this activity has been planned and implemented by the Association for the Advancement of Blood & Biotherapies (AABB) and CME Outfitters, LLC. CME Outfitters LLC. is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

    Physicians (ACCME): CME Outfitters, LLC, designates this live activity for a maximum of one (1) AMA PRA Category 1 CreditTM. CME Outfitters, LLC, designates this enduring activity for a maximum of one (1) AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Claiming Credit
    Live Activity - Upon completion of the live activity, you will receive instructions to complete your evaluation, which is necessary to claim credit and receive your certificate of attendance/completion (credit must be claimed by the date provided in the instructions). The evaluation can be found by logging into the AABB Education Platform.

    Enduring Activity - Once the enduring (on-demand) program is available, you will receive instructions to access the AABB Education Platform. Upon completion of viewing the enduring activity, you will need to complete the evaluation, which is necessary to claim credit and receive your certificate of completion (credit must be claimed by the date provided in the AABB Education Platform).

    Program & Credit Expiration Dates:

    • Live Activity Program Date: April 26, 2023; Credit Expiration Date: May 26, 2023
    • Enduring Activity Program Dates: April 26, 2023 – April 25, 2026; Credit Expiration Date: April 25, 2026

    Disclosure Declaration

    It is the policy of CME Outfitters, LLC, and the Association for the Advancement of Blood & Biotherapies to ensure independence, balance, objectivity, and scientific rigor and integrity in all of their CE activities. Faculty must disclose to the participants any relationships with commercial companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. CME Outfitters, LLC, has evaluated, identified, and mitigated any potential conflicts of interest through a rigorous content validation procedure, use of evidence-based data/research, and a multidisciplinary peer review process. The following information is for participant information only. It is not assumed that the presence of such relationships will have a negative impact on the presentations.

    Disclosures for the planners of this event can be found here. Disclosures for the program faculty, peer reviewers, and CME Outfitters, LLC. personnel are provided at the beginning of the program.

    Faculty Biographies

    Sunitha VegeSunitha Vege is the Technical Director of the Genomics Laboratory at the New York Blood Center. She received her Master’s in Ecology and Evolutionary Biology and more recently, in Bioinformatics. She has been working in the blood group genotyping field for over 15 years with particular interest in the RH system and its genetic diversity. She has presented at state and national meetings and as co-authored numerous publications in the area.

    Dr. David UnoldDr. David Unold serves as Health Sciences Associate Clinical Professor at UC Davis, Sacramento and believes in providing evidence-based and cost-effective patient care. His specialties include transfusion medicine, apheresis, and special coagulation. His interests are in the diagnosis and treatment of bleeding and clotting disorders. Dr. Unold is board certified by the American Board of Pathology, Blood Banking/Transfusion Medicine, Board Certified, 2014; American Board of Pathology, Clinical Pathology, Board Certified, 2014; and, CA Medical Board, License, Licensed, 2014. He received his undergraduate degree in Biomedical Science from Marquette University, his medical doctorate from the Medical College of Wisconsin, and completed his residency in pathology at Baystate Medical Center/Tufts University School of Medicine. Dr. Unold completed a fellowship in Blood Banking/Transfusion Medicine at Yale-New Haven Hospital. His professional memberships include the American Society for Apheresis, American Society for Clinical Pathology, Association for the Advancement of Blood & Biotherapies, Christian Medical and Dental Association, and the College of American Pathologists.