Scientific Research Grant Award Recipients

The 2023 early-career grant cycle marks 40 years that the AABB Foundation has awarded research funding to early-stage investigators! Since its inception, the Foundation has awarded over $11 million to early-career investigators through its Scientific Research Grants Program.

The Foundation awards grants for investigator-initiated original research in all aspects of blood banking, transfusion medicine, biotherapies and patient blood management on the basis of their scientific merit, relevance, impact, focus and appropriateness to the scope of funding, and likelihood of yielding meaningful data.

Examples of topics are presented with our gallery of grant and scholar award recipients.

Many AABB Foundation early-career grant recipients have become leaders in their field and are recognized in the Foundation Hall of Fame.

The AABB Foundation is pleased to announce our 2022 early-career Scientific Research Grant award recipients! 2023 recipients will be announced in July.


AABB Foundation Early-Career Scientific Research Grant Logo

2022 AABB Foundation Scientific Research Grant Award Recipients

Susan R. Conway, MDSusan R. Conway, MD

Assistant Professor
Department of Pediatrics
Children's Research Institute

Project Title: “Harnessing the naïve T-cell compartment to generate multi-antigen-specific SARS-CoV-2-specific T-cells”

Project Summary: This project evaluates the cytolytic function, polyfunctionality and epitope specificity of SARS-CoV-2-specific T cells (CSTs) derived from memory and naïve donor T cells against circulating SARS-CoV-2 variants. This comprehensive product evaluation is critical as we proceed with a clinical trial evaluating our donor-derived CST product (IND 27588). Moreover, this work will enhance development of off-the-shelf CST products for the treatment of SARS-CoV-2 infection in immune suppressed patients.


Mark N. Lee, MD, PhDMark N. Lee, MD, PhD

Research Fellow
Department of Pathology
Dana-Farber Cancer Institute

Project Title: “Identification of T cell epitopes in hemophilia patients with inhibitors using next-generation mapping technologies”

Project Summary: The development of coagulation factor inhibitors is the major complication of factor replacement therapy for hemophilia patients, leading to increased morbidity and mortality. Here, I propose to identify factor peptides necessary for T cell recognition, utilizing a novel epitope identification technology that enables synthesis and pooled testing of thousands of peptides to decipher immunogenic epitopes. These results will further the path towards development of less immunogenic factor proteins.


Yunfeng Liu, PhDYunfeng Liu, PhD

Research Scientist
Laboratory of Complement Biology, Lindsley Kimball Research Institute
New York Blood Center

Project Title: “Mechanisms of interferon activation and mononuclear phagocyte expansion in sickle cell disease”

Project Summary: Intravascular hemolysis, a hallmark of sickle cell disease (SCD), is increasingly recognized as contributing to SCD pathophysiology. We recently showed that hemolysis induces inflammatory type I interferon (IFN-I) production by liver macrophage/monocytes, causing phagocyte activation and expansion and exacerbating transfused antibody-coated RBC destruction in SCD. In this proposal, we will test the mechanism of hemolysis-induced IFN-I production and IFN-I-driven macrophage expansion in SCD.


Mara Pavel-Dinu, PhDMara Pavel-Dinu, PhD

Instructor
Pediatrics
Stanford University

Project Title: “Discovery of mechanisms supporting the long-term regenerative potential of CRISPR/Cas9 – AAV6 genome targeted human hematopoietic stem cells”

Project Summary: Genetically corrected HSCs, using CRISPR/Cas9-AAV6 platform, have the enormous potential to become a curative and durable therapy for many non-malignant diseases. However, following ex vivo culture and gene correction procedure, the derived genetically modified HSCs show diminished (4- to 90-fold) long-term regenerative potential. Here, we will identify biological and environmental factors for devising a new ex vivo culturing setting supportive of multipotent genetically corrected HSCs.


W. Alton Russell, MS, PhDW. Alton Russell, MS, PhD

Assistant Professor
Department of Epidemiology Biostatistics and Occupational Health, School of Population and Global Health
The Royal Institution for the Advancement of Learning/McGill University

Project Title: “Tailoring blood donation intervals to individual risk in South Africa, the Netherlands, and the United States”

Project Summary: Minimum inter-donation intervals aim to manage risk of iron deficiency and hemoglobin deferrals in repeat blood donors. Using operational data from South Africa, the Netherlands, and the United States, we aim to develop and analyze new policies that tailor the minimum inter-donation interval to each blood donor’s estimated risk of deferral or low/absent iron. Our tailored minimum inter-donation intervals could efficiently protect high-risk donors without unduly restricting the blood supply.


Liang Zheng, PhDLiang Zheng, PhD

Research Assistant Professor
Pathology and Laboratory Medicine
University of Kansas Medical Center Research Institute, Inc.

Project Title: “Ankrd26, Thrombocytopenia 2 and TTP”

Project Summary: Inherited thrombocytopenia 2 (THC2) is an autosomal dominant disorder involving the ANKRD26 gene. Distinguishing THC2 from other causes of thrombocytopenia is crucial for patient care. The mechanism(s) of thrombocytopenia in THC2 patients are not yet clear. In addition, we have recently discovered a link between mutations in ANKRD family members and immune thrombotic thrombocytopenic purpura (iTTP). We propose to use a zebrafish model we developed to explore the role of ANKRD26 in THC2 and iTTP.


Past Recipients of the AABB Foundation Scientific Research Grant Award

2021

Alma-Martina Cepika, MD, PhD
Leland Stanford Junior University
“Personalized Tr1 Cell-Based Therapy for Graft-vs-Host Disease”

Simon J. Cleary, PhD
University of California, San Francisco
“New Approaches to Study and Treat Alloantibody-Mediated Diseases Resulting from Blood Transfusions”

Pietro Genovese, BSc, MSc, PhD
Dana-Farber Cancer Institute
“Engineering Immunotherapy Resistant Hematopoiesis to Treat High-Risk Acute Myeloid Leukemia”

Panagiotis Mistriotis, PhD
Auburn University
“Eliminating Senescent Bone Marrow-Derived Mesenchymal Stem Cells Using Microfluidics”

Jansen N. Seheult, MB BCh BAO, MSc, MS, MD
University of Pittsburgh School of Medicine
“A Stochastic, Multicompartment, Dynamic Model of Hemostasis and Oxygenation During Trauma Resuscitation: Building a Platform for in Silico Trials of Transfusion Strategies”

2020

Annamaria Aprile, PhD
Ospedale San Raffaele
"Exploring the role of FGF23 in β-thalassemia: a novel target to ameliorate bone marrow microenvironment and anemia"

Agnieszka Czechowicz, MD, PhD
Stanford University
"Determine genetic factors and mutations that regulate progression to bone marrow failure and myeloid neoplasia in Fanconi anemia"

Areum Han, PhD
Boston Children’s Hospital
"The role of the RNA editor-exonuclease axis in RNA turnover during erythropoiesis: from mouse embryo studies to in vitro modeling"

Robert H. Lee, PhD
University of North Carolina
"Efficacy of platelet transfusion in the setting of anti-platelet therapy"

Larry Luchsinger, PhD
New York Blood Center
"Caveolae Coordination of Signal Transduction Pathways in Hematopoietic Stem Cell Function"

Evan Orenstein, MD
Emory University
"Improving Patient Blood Management in Pediatrics through Automated Medical Error Detection and Clinical Decision Support Design"

David Roh, MD
Columbia University
"Red Blood Cell Contribution to Coagulopathy and Cerebral Oxygenation after Intracerebral Hemorrhage"

Kim Vanuytsel, PhD
Boston Medical Center
"Validation of a potential curative gene editing approach across the diverse sickle cell disease (SCD) patient population using induced pluripotent stem cells (iPSC)”

2019

Delfim Duarte, MD, PhD
Instituto de Biologia Molecular e Celular (IBMC)
"Targeting the Bone Marrow Vascular Microenvironment to Improve Hematopoietic Stem Cell Therapies in Acute Myeloid Leukemia"

Saba Ghassemi, PhD
University of Pennsylvania
"Redirecting Quiescent T cells with Chimeric Antigen Receptors (CARs) for Adoptive Immunotherapy"

Marie Hollenhorst, MD, PhD
Stanford University
"CMP-Neu5Ac: A Central Molecule in Bleeding Diseases and Mediator of a Novel Platelet Effector Function"

Tiffany Thomas, PhD
Columbia University Medical Center
"The Effect of Dietary Lipids on Red Cell Lifespan and Recovery"

Francesca Vinchi, PhD
New York Blood Center
"Role of Heme-Activated Macrophages in Acute Chest Syndrome"

Yan Zheng, MD, PhD
St. Jude Children's Hospital
"Comprehensive Characterization of RH Loci by Whole Genome Sequencing and Long-read Genome Sequencing"

2018

Arunoday K. Bhan, PhD
Boston Children's Hospital
“Identifying megakaryocyte maturation pathways critical for platelet generation.”

Vijay G. Bhoj, MD, PhD
University of Pennsylvania
“Dissecting the Humoral Response to FVIII for Therapeutic Applications.”

Avital Mendelson, PhD
Lindsley F. Kimball Research Institute
New York Blood Center
“A biomimetic niche for platelet formation in vitro.”

Antonella Nai, BSc, MSc, PhD
Ospedale San Raffaele, Italy
“Targeting the second transferrin receptor for amelioration of severe malarial anemia.”

Robert S. Nickel, MD, MSc
Children's Research Institute
“Hydroxyurea and Transfusion (HAT): Pilot Study of Combination Therapy for Patients with Sickle Cell Anemia.”

Hideyuki Oguro, PhD, MSc, BSc
The Jackson Laboratory
“Induction of hematopoietic stem cell proliferation and mobilization by estrogen receptor signaling.”

Moritz Stolla, MD, PhD
Bloodworks Northwest Research Institute
“Cold-stored Platelets for the Reversal of Dual Antiplatelet Therapy.”

2017

Benjamin Samelson-Jones, MD, PhD
Children’s Hospital of Philadelphia
“Novel Therapeutics for Hemophilia B: A Rational Pursuit of Bioengineered Factor IX Variants with Enhanced Clotting Activity”

Juliana Xavier-Ferrucio, PhD
Yale University
“Megakaryocyte erythroid progenitor fate specification under iron and oxygen deficiency”

2016

Angelo D’Alessandro, PhD
University of Colorado Denver – Anschutz Medical Campus
“The role of adenosine signaling in the preservation of energy metabolism of stored erythrocytes”

David Gibb, MD, PhD
Yale University School of Medicine
“Characterizing innate immune mechanisms underlying the link between inflammation and RBC alloimmunization”

Mobin Karimi, MD, PhD
University of Pennsylvania
“Separation of GVHD from GVT responses by modulation of T cell signaling pathways”

Troy Lund, MD, PhD
University of Minnesota
“Adipokine Regulation of Hematopoietic Cell Homing”

Sandhya Panch, MBBS, PPH
National Institutes of Health
“Barcoded macaque transplants: A novel approach to study Human Umbilical Vein Endothelial Cell (HUVEC) expanded hematopoietic stem and progenitor cell (HSPC) engraftment and repopulation kinetics”

2015

James Ankrum, PhD
The University of Iowa
“Elucidating the role of FOXO3 in restoring the potency of in vitro expanded mesenchymal stem cells.”

Yacine Boulaftali, PhD
Inserm, U1148- Laboratory for Vascular Translational Science (LVTS), France
“Neutralizing serpinE2: a new medical concept of treating haemophilia.”

Lindsey A. George, MD

University of Pennsylvania, Perelman School of Medicine
“Prothrombin activation in vivo: contribution of membrane binding for effective hemostasis and development of a novel warfarin reversal strategy.”

Sarika Saraswati, PhD
Vanderbilt University
“New Strategies to Augment Efficacy of Stem Cell Therapy for Therapeutic Revascularization”.

William Savage, MD, PhD
Brigham and Women’s Hospital
“Aeroallergen-specific antibodies in allergic transfusion reactions.”

2014

Ramesh Nayak, PhD
Hoxworth Blood Center (HBC), Cincinnati Children’s Hospital Medical Center (CCHMC) 
“Angiotensin in stem cell recruitment and mobilization”

Richard Francis, MD, PhD
Columbia University Medical Center
“Effect of glucose-6-phosphate dehydrogenase deficiency on red blood cell storage”

Neil Hanchard, MD, PhD
Baylor College of Medicine
“A genomics approach to transfusion responders in sickle cell disease”

Krystalyn Hudson, PhD
Bloodworks Northwest Research Institute
“Establishment and maintenance of lymphocyte tolerance to red blood cell antigens”

Julie Peterson, PhD
Blood Research Institute, BloodCenter of Wisconsin
“Recombinant glycoprotein fragments for improved detection of alloantibodies in Neonatal Alloimmune Thrombocytopenia (NAIT)”

Claude Tayou Tagny, MD, MS, MSc
University of Yaoundé, Cameroon
“Risk Factors of HIV infection in Sub-Saharan Africa blood donor – A pilot phase in Cameroon”

2013

Stella T. Chou, MD
University of Pennsylvania, Perelman School of Medicine
“Red blood cell generation from human induced pluripotent stem cells: a new tool for transfusion medicine”

William Janssen, MD
National Jewish Health, University of Colorado Denver
“Degradation of the Pulmonary Endothelial Glycocalyx in Transfusion Related Acute Lung Injury (TRALI)”

George J. Murphy, PhD
Center for Regenerative Medicine (CReM)
“Pluripotent stem cells in the modeling of blood disease and the development of potentially transfusable human red blood cells and platelets”

Robert B. Neuman, MD
Emory University School of Medicine
“Physiologic effects of RBC storage in chronic transfusion recipients: vasoreactivity, exercise capacity, and oxygen consumption”

Sean Stowell, MD, PhD
Emory University School of Medicine
“Characterization of Immunity and Tolerance Following RBC Transfusion”

2012

Stephanie Eisenbarth, MD, PhD
Yale University, Laboratory Medicine and Internal Medicine
“Identifying Innate Immune System Pathways Critical for RBC Alloimmunization”

Anand Padmanabhan, MD, PhD
BloodCenter of Wisconsin
“Role of IgA and IgM Immunoglobulins in Heparin-Induced Thrombocytopenia and Thrombosis (HIT)”

Tracey L. Papenfuss, DVM, MS, PhD
Ohio State University, Waxner Medical Center, Regenerative Medicine
“Development of myeloid derived suppressor cell therapy for the treatment of inflammatory disease”

Michael Nemeth, PhD
Roswell Park Cancer Institute
“Improving Bone Marrow Transplantation Through Targeting Hematopoietic Stem Cell Quiescence”

Henrique Viega-Fernandes, DVM, PhD
Instituto de Medicina Molecular (IMM), Portugal
“Modulation of RET Signaling in Hematopoietic Stem Cell Transplantation”

Jianhua Yu, PhD
The Ohio State University
“Preclinical Studies of the Combination of Recombinant Human FLT3 Ligand and AMD3100 to Mobilize Allogeneic Blood Cell Grafts for Transplantation”

2011

Attilio Bondanza, MD, PhD
H San Raffaele, Italy
“Cell Therapy of Multiple Myeloma by Genetic Redirection of T Cells Against CD44v6”

Mettine H.A. Bos, PhD
Leiden University Medical, Netherlands
“Mechanisms Regulating the Macromolecular Enzyme Complex Assembly in Blood Coagulation”

Swapan Kumar Dasgupta, PhD
Baylor College of Medicine
“Signaling Cascade Leading to Phosphatidylserine Exposure in Stored Platelets”

Eldad Hod, MD
Columbia University Medical Center
“Effect of Repeat Blood Donation on Atherosclerosis and Cancer Risk in Murine Models”

Katherine MacNamara, PhD
Albany Medical College
“IFNγ-Mediated Control of Hematopoietic Stem and Progenitor Cell Differentiation”

Nilam Mangalmurti, MD
University of Pennsylvania
“Role of Red Cell Advanced Glycation End products in Endothelial Dysfunction”

2010

Julie Audet, PhD
University of Toronto, Canada
“Directed Expansion and Differentiation of Blood Progenitor Cells using TAT-Conjugated Transcription Factors”

Rachel Bercovitz, MD
The University of Colorado, Denver
“Transfusion-related Acute Lung Injury (TRALI) from Plasma Products: Understanding the Pathogenesis of Immune- and Non-Immune-Mediated TRALI and Determining Methods to Mitigate TRALI Risk”

Jonathan Finn, PhD
Children's Hospital of Philadelphia
“The Development and Safety Characterization of Novel Hyper-functional Factor IX Variants for the Treatment of Hemophilia B”

Peter Ghoroghchian, MD, PhD
University of Pennsylvania
“Fundamental Design and Characterization of Nanoscale Polymersomes as Advanced Hemoglobin-based Oxygen Carriers”

Mariluz Mojica Henshaw, PhD
University of Utah
“Development of a Xeno-free Microcarrier-based Human Mesenchymal Stem Cell Expansion System”

Jill Johnsen, MD
Puget Sound Blood Center
“The Role of Blood Group Antigens in Von Willebrand Factor Homeostasis”

Bartolomeu Nascimento, MD
Sunnybrook Health Sciences Centre, Toronto
“Trauma Resuscitation Formula-driven versus Laboratory-guided Transfusion Study (TRFL): Coagulopathy Substudy”

Sergey Shevkopyas, PhD
Tulane University
“The Relationship between the Ability of Stored Red Blood Cells to Perfuse Microvascular Networks and their 24-hr Post-Transfusion Recovery in Vivo”

2009

Alicia Barcena, PhD
University of California San Francisco
“Evaluation of human fetal membranes as a source of hematopoietic stem cells.”

Daniel Gonzalez-Nieto, PhD
Cincinnati Children's Hospital Medical Center
“Connexin-43 in the hematopoietic stem cell niche.”

Taku Kambayashi, MD, PhD
University of Pennsylvania
“The role of GMCSF in regulatory T-cell proliferation and homeostasis.”

Chance John Luckey, MD, PhD
Brigham and Women's Hospital Blood Bank
“Directed differentiation of embryonic stem cells by regulated caspase9 cleavage of zona-occludens2.”

Nicolas Pineault, PhD
Héma-Québec, Canada
“A cellular-based therapy to prevent or reduce thrombocytopenia.”

Ayaz Rahman, MD
Emory University
“The effects of fresh versus older RBC transfusions in subjects with cardiovascular disease.”

Rahima Zennadi, PhD
Duke University Medical Center
“Regulation by nitric oxide of sickle red cell adhesion.”

2008

Hava Avraham, PhD
Harvard Institute of Medicine, Beth Israel Deaconess Medical Center
“Hematopoietic Stem Cell Mobilization by Cannabinoids”

Rose Beck, MD, PhD
Case Western Reserve University School of Medicine
“Notch-induced NK Cells for Cell Therapy in Hematologic Maligancy”

Christine M. Cserti-Gazdewich, MD, FRCP
University of Toronto, Canada
“Cytoadherence in Pediatric Malaria (CPM) Study.”

Nobuharu Fujii, MD, PhD
Fred Hutchinson Cancer Research Center
“Identification of Novel H-Y Antigens using Artificial Neural Network”

Mark R. Looney, MD
University of California, San Francisco
“The Role of Platelets in Experimental Transfusion-related Acute Lung Injury (TRALI)”

Adam Munday, MD PhD
Puget Sound Blood Center
“Platelet Cold Receptors: Potential for Improving Platelet for Improving Cold Storage”

Beth Shaz, MD
Emory Center for Transfusion and Cellular Therapies, Emory University School of Medicine
“Blood Donation considerations in African Americans”

2007

Spero Cataland, MD
The Ohio State University
“A Randomized Study of Concurrent Cyclosporine and Plasma Exchange versus Concurrent Corticosteroids and Plasma Exchange as the Initial Therapy of Thrombotic Throbocytopenic Purpura”

Peiman Hematti, MD
University of Wisconsin-Madison
“ESC-derived MSC transplantation in NOD/SCID mice”

Cheryl Ann Lobo, PhD
New York Blood Center
“Role of Red Cell Glycophorins in the Invasion of Babesia divergens”

A. Louise McCormick, PhD
Emory University School of Medicine
“The role of cytomegalovirus-encoded inhibitor of caspase-8 activation, vICA, in disease following transfusion or transplantation”

Michael Milson, PhD
Cincinnati Children's Hospital Medical Center
“Genetic correction of the Fanconi Anemia stem cell defect”

Lirong Qu, MD, PhD
University of Pittsburgh
“Detection and Quantification of Human Herpesvirus 8 (HHV-8) Genomes in US Blood Donors with Sensitive real-time PCR”

Astrid Van Halteren, MD, PhD
Leiden University Medical Center, Netherlands
“Pregnancy-Induced Minor Histocompatibility Alloimmune T Cells and Fetal Microchimerism: Friends of Foes?”

Saul Yedgar, PhD
Hebrew University of Jerusalem, Israel
“Repair of red blood cell flow properties for transfusion therapy: the effect fo leukoreduction and rejuvenation”

2006

Kent W. Christopherson II, PhD
University of Texas Health Science Center, Houston
“CD26 Inhibition As A Method Of Improving Hematopoietic Stem Cell Transplant Efficiency”

Jeanne E. Hendrickson, MD
Emory University School of Medicine
“Effect Of Host Inflammation On Alloimmunization To RBC Transfusion”

Lana Kaiser MD, DVM
Michigan State University
“Transfusion Iron Overload And Cardiac Arrhythmias”

Marcus O. Muench, PhD
Blood Systems Research Institute
“In Utero Transplantation of The Hematopoietic Microenvironment”

Eric M. Ostertag, MD, PhD
University of Pennsylvania
“Cloning and Characterization of Monoclonal Anti-ADAMTS13 Autoantibodies from Patients with Thrombotic Thrombocytopenic Purpura (TTP)”

Robert Paulson, PhD
Penn State University
“Role Of BMP4 Signaling On Short-Term Radioprotection”

Jill Storry, PhD
Lund University, Sweden
“Characterization of the Vel Blood Group System”

Leon L. Su, MD
Emory University
“Recipient Kinetics and the Role of Host Factors in Transfusion-Transmitted Cytomegalovirus (TTCMV) Infection”

Lan Zhou, PhD
Case Western Reserve University
“Regulation of Granulopoiesis by Fucosylated Glycans Through Selectin-Mediated Adhesion and Fringe-Modified Notch Signaling Pathways”

Xianzheng Zhou, MD, PhD
University of Minnesota Cancer Center
“Adoptive Cord Blood T Cell Therapy Of Leukemia By The Sleeping Beauty Transposon”

2005

Marie Bleakley, MD
Fred Hutchinson Cancer Research Center
“Discovery of Antigens for Targeted Therapy of Leukemia”

Jose Cancelas, MD, PhD
Cincinnati Children's Hospital Medical Center
“Mobilization of Hematopoietic Stem Cells by Reversible Inhibition of Rac-Type Rho GTPases: Demonstration of Proof-of-Concept for Future Clinical Applications”

Li Chai, MD
Brigham and Women's Hospital
“A Novel Intracellular Pathway of WT1/HSAL2 in Leukemogenesis”

Brian S. Custer, MPH, PhD
Blood Systems Research Institute
“Retrospective Cohort Analysis of Return Behavior in Temporarily Deferred and Eligible Voluntary Blood Donors”

Craig E. Daniels, MD
Mayo Clinic College of Medicine
“The Accuracy of Natriuretic Peptides (BNP and N-pro-BNP) in the Differentiation Between Transfusion Related Acute Lung Injury (TRALI) and Transfusion Related Circulatory Overload (TACO)”

Allison Hubel, MS, PhD
University of Minnesota
“Post Thaw Processing of Hematopoietic Stem Cell Products”

Andrew Mackin, BVMS, MVS, DVSc, FACVSc, Diplomate ACVIM
Mississippi State University
“Evaluation of the Efficacy of Phototreatment of Packed Red Blood Cells at Preventing Transfusion-Associated Transmission of Babesiosis In Dogs”

Nora Ratcliffe, MD
VAMC White River Junction and Manchester
“The Role of Dendritic Cell Subsets in Autoimmune Myocarditis and the Potential for Cytotherapy”

Steven R. Sloan, MD, PhD
Children's Hospital Boston
“Role of the CCL4 Chemokine in the Immune Response to Red Cell Transfusions: Implications for Immunosuppressive Therapy”

2004

Ognjen Gajic, MD
Mayo Clinic
“Transfusion-Related Acute Lung Injury in the Medical Intensive Care Unit”

Andres Hidalgo, PhD
Mount Sinai School of Medicine
“Optimizing Cord Blood Transplantation by Upregulation of Selectin Ligands”

Qizhen Shi, MD, PhD
Medical College of Wisconsin
“Targeting Human Platelet Glycoprotein Ibα Gene Expression to the Platelets of Bernard-Soulier Syndrome Mice”

X. Long Zheng, MD, PhD
Children's Hospital of Philadelphia
“Characterization of Autoantibodies Directed Against ADAMTS13 Metalloprotease Underlying Thrombotic Thrombocytopenic Purpura”

James C. Zimring, MD, PhD
Emory University School of Medicine
“Selective Induction of Allotolerance in Bone Marrow Transplantation”

2003

Laura Cooling, MD, MS
University of Michigan
“Molecular Analysis of Globo- and Lacto-Family Glycosyltransferases: Molecular Etiology of the LKE-Negative and LKE-Weak Phenotypes”

Yvonne H. Datta, MD
Medical College of Wisconsin
“Genetic Mapping and Characterization of the Bleeding Disorder in the Fawn-Hooded Hypertensive Rat”

Carl S. Goodyear, PhD
University of California San Diego
“Mechanisms of Immunomodulation by Protein A Pheresis”

Suresh Shelat, MD, PhD
University of Pennsylvania
“Characterization of the Human Immune Response in Heparin-Induced Thrombocytopenia Using Repetoire Cloning”

Steven L. Spitalnik, MD
Columbia University
“Hemolytic Transfusion Reactions: A Transgenic Mouse Model”

Scott S. Tykodi, MD, PhD
Fred Hutchinson Cancer Research Center
“Identification of Antigens Mediating Graft-versus-Tumor Effects Following MHC-Identical Allogeneic Hematopoietic Cell Transplantation”

2002

Larry J. Dumont, MBA
Gambro BCT
“Human Cytomegalovirus (HCMV) Reactivation – Human Exposure Model and Mechanism D”

Michael Hodsdon, MD, PhD
Yale University
“Regulation of von Willebrand Factor Susceptibility to Proteolytic Cleavage by a Plasma Metalloproteinase”

Lennart Logdberg, MD, PhD
Emory University
“Use of Bone Marrow Stem Cells for Pancreatic Islet Repopulation and Regeneration”

Una O'Doherty, MD, PhD
University of Pennsylvania
“Regulation of HIV-1 Latency in Resting T Cells by Dendritic Cells”

2001

Maria Bettinotti, PhD
National Institutes of Health
“Molecular Basis of Polymorphisms in Neturophil Antigen NB1: CD177”

Sandra L. Haberichter, PhD
Blood Research Institute; Blood Center of SE Wisconsin
“The Role of the von Willebrand Factor Propeptide in Targeting vWF to the Regulated Storage Pathway”

Jonathan David Kurtis, MD, PhD
Brown University
“Novel Erythrocyte Invasion Protiens As Vaccines For Human Falciparum Malaria”

Peter L. Perrotta, MD
SUNY @ Stony Brook
“Role Of Apoptotic Mechanisms In Platelet Dysfunction And Death”

2000

Walter L. Biffl, MD
Denver Health Medical Center
“Blood Transfusion-Provoked Delay in Neutrophil Apoptosis in Trauma may be Altered by Modifying Transfusion Practices”

Jeffrey L. Carson, MD
UMDNJ-Robert Wood Johnson Medical School
“The Effect of Anemia and Transfusion on Postoperative Delirium”

Thomas H Fischer, PhD
University of North Carolina, Chapel Hill
“Hyperbaric Freezing for the Preparation of Rehydrated, Lyophilized Platelets”

James D. Gorham, MD, PhD
Dartmouth Medical School
“T Cell Cytokine Secretion in a Murine Model of Transfusion-associated ImmunoModulation (TRIM)”

Patricia Kopko, MD
Sacramento Medical Foundation Blood Centers
“The Association of HLA Class II Antibodies and White Blood Cell Activation with Transfusion-Related Acute Lung Injury”

Krista V. Lankford, MD
Emory University
“Mechanisms of Action of Therapeutic Plasma Exchange (TPE) in Thrombotic Metalloprotease (MP) and Its Antibody Inhibitor (IMP)”

Karina Yazdanbakhsh, PhD
New York Blood Center
“Recombinant Antigens as Tools for Identification of Alloantibodies in Patients' Sera”

1999

David G. Meyers, MD
Kansas University Medical Center
“A Historical Cohort Study of the Effect of Lowering Body Iron Through Blood Donation on Cardiac Events”

Andrey Skripchenko, PhD
Holland Laboratory, American Red Cross
“The Mechanism(s) of virus Photoinactivation by Dimethylmethlene Blue”

Connie Westhoff, PhD
University of Pennsylvania
“Deciphering the Function of the Rh Proteins”

1998

Douglas P. Blackall, MD
University of California, Los Angeles
“Recombinant Blood Group Antigen Engineering: Glycophorin A as a Model Glycoprotein”

Raymond L. Comenzo, MD
Boston Medical Center
“Immunoglobulin Genes And DNA Vaccines: Synergy With Stem-Cell Transplant?”

Robertson Davenport, MD
University of Michigan
“A Murine Model of Acute Hemolytic Transfusion Reactions”

Timothy C. Fisher, MB, Ch.B
USC School of Medicine
“Red Blood Cell Antigen Masking by Covalently-Bound Polyethylene Glycol”

Peter Larson, MD
University of North Carolina, Chapel Hill
“The Role of the GIA Domain in the Function of Vitamin K-dependent Coagulant Proteins”

Eleanor Pollack, MD
The Children's Hospital of Philadelphia
“Substrate and Inhibitor Binding Sites of Human Coagulation Factor Xa”

Jo Anna Reems, PhD
Blood Systems Foundation
“Ex Vivo Expansion of Human Umbilical Cord Blood Hematopoietic Progenitor Cells: Evaluation of their Function in a Mouse Transplant Model”

John Donald Roback, MD, PhD
Emory University Hospital
“The Role of Leukocytes in Transfusion-Transmitted Cytomegalovirus (TT-CMV) Infection: Development of an Animal Model”

John Rosenberg, PhD
Blood Center of Southeast Wisconsin
“Impact of von Willebrand Factor on Factor VIII Gene Targeting”

1997

Scott Burger, MD
University of Minnesota, Minneapolis
"Adhesive Interactions in Hematopoietic Cell Homing"

Petr Jarolim, MD
Brigham and Women's Hospital
"Characterization of Blood Group Antigens Carried by Erythroid Band 3"

Diane Krause, MD, PhD
Yale University School of Medicine
"Regulation of Cd34 Expression During Hematopoiesis"

Stanley J. Naides, MD
University of Iowa
"Structure-Function Relations in Parvovirus B19 Binding to Solid Phase Immobilized Glyosphingolipid Cell Receptor"

Christopher Silliman, MD, PhD
Bonfils Blood Center
"The Pathophysiology of Transfusion Related Acute Lung Injury in an Animal Model and In Vitro Investigation of Endothelium as an Active Participant"

Dorothea Zucker-Franklin, MD
New York University Medical Center
"Studies on Prevalence and Transmissibility of HTLV-I/II Tax" 

1996

Emily Baron-Casella, PhD
The Johns Hopkins University School of Medicine
"Identification of the Epitopes and Antibodies Involved in the HPA-3 (Bak) and HPA-4 (Pen) Alloantigen Systems"

Tylis Y. Chang, MD
University of Pennsylvania
"ABO Antibodies: The Ontogeny of the "Natural Repertoire"

Laura Cooling, MD
University of Iowa
"Population Differences in Blood Group Antigen Expression Among Normal Platelet Donors"

Loren D. Fast, PhD
Rhode Island Hospital
"The Immunological Consequences of Blood Transfusion: Early Events"

Karen E. King, MD
The Johns Hopkins Hospital
"The Role of Complement and Complement Inhibitors in Delayed Hemolytic Transfusion Reactions"

Louis V. Kirchhoff, MD
University of Iowa
"Use of Recombinant Trypanosoma Cruzi Proteins for Serologic Diagnosis of Chagas Disease"

Joni M. Lohmann, MD
Veterans Affairs, Medical Center
"Nonisotopic Analysis of the Survival Characteristics of Multiple Concurrent Platelet Populations with a Biotin Label"

Jack T. Stapleton, MD
University of Iowa
"Detection of Hepatitis C Virus RNA in the Whole Blood of Volunteer Blood Donors with and Without Elevated Alanine Transanimase"

Neil Young, Msc, FIBMS
University of Oxford, England
"Molecular Analysis of Alloreactivity in Recipients of HLA-One-Haplotype-Matched or Fully HLA-Mismatched Pre-Transplant Blood Transfusions"

1995

Francesco Bertolini, MD, PhD
Maugeri Foundation, Pavia Medical Center, Italy
"Collection and Ex-Vivo Expansion of Placental Blood-Derived Hematopoietic Progenitors for Transplantation"

Brian Curtis, BS, MT(ASCP)SBB
The Blood Center of Southeastern Wisconsin
"Role of ABO Blood Group Incompatibility in the Pathogenesis of Neonatal Alloimmune Thrombocytopenic Purpura"

Louis A. DePalma, MD
The George Washington University Medical Center
"Gene Expression in Activated Cord Lymphocytes: Relevance to Neonatal Immunohematology"

Susan H. Eshleman, MD, PhD
Case Western Reserve University
"Regulation of Protein Glycosylation: Characterization of Glycosylation Signals for Recombinant Protein Design"

Malcolm R. MacKenzie, MD
Sacramento Medical Foundation Center for Blood Research
"Immunoregulatory B Cells in Transfusion"

Martha Osborne
Central Kentucky Blood Center
"Retaining First Time Donors: Testing the Effectiveness of Interventions Designed to Increase Personal Perception as a Committed Donor"

Robert I. Roth, MD, PhD
Department of Veterans Affairs Medical Center
"A Mechanism for Endothelial Cell-mediated Thrombosis: Deleterious Consequences of the Interaction of Cell-free Hemoglobin and Bacterial Endotoxin"

Gerald Soslau, PhD
Hahnemann University
"Response of Stored Platelets to Paired Agonists in the Presence and Absence of Extracellular ATP"

Connie Westhoff, PhD
University of Nebraska, Lincoln
"Targeted Deletion of the Rh Genes in Human Erythroleukemia Cells"

Theodore Wun, MD
University of California Davis Cancer Center
"Thrombopoietin Effects on Human Platelets"

1994

Douglas P. Blackall, MD
University of Tennessee
"Human Blood Group Glycophorins as Receptors for the Plasmodium falciparum Malaria Parasite"

Paul F. Bray, MD
The Johns Hopkins University School of Medicine
"Application of Novel Molecular Methods to Genotype and Identify New Platelet Specific Antigens"

Umakant J. Dumaswala, PhD
Hoxworth Blood Center
"Glutamine Improves Red Cell Preservation"

Walter H. Dzik, MD
New England Deaconess Hospital
"Transient Microchimerism Following Allogeneic Blood Transfusion"

Cheng-Han Huang, MD, PhD
New York Blood Center
"Studies on Human S-s-U and S-s-U+ Red Blood Cells–Molecular Basis, Phenotypic Heterogeneity and Relationship to Other Surface Markers of Glycophorin"

Maryanne Keashen-Schnell
American Red Cross Blood Services
"Antibody Detection in the Thrombocytopenic Disorders of Pregnancy"

Alan H. Lazarus, PhD
St. Michael's Hospital, Canada
"Study of a B-cell Regulatory Pathway to Delay or Prevent Platelet Alloimmunization in a Human-PBMC-SCID Mouse Model"

Christine S. Rinder, MD
Yale University School of Medicine
"An In Vitro Model of the Effects of Platelet Transfusion on Leukocyte Function"

S.M. Hossein Sadrzadeh, PhD
New England Deaconess Hospital
"Oxygen Free Radical Damage of Gamma-Irradiated Blood"

1993

Jeffrey L. Carson, MD
UMDNJ – Robert Wood Johnson Medical School
"Cost Effectiveness of Autologous Blood Transfusion"

Scott Cobourn, PhD
Duke University Medical Center
"Regulation of CD44 Expression in Erythroid Cells"

Ellen P. Klohe, PhD
Inland Northwest Blood Center
"Effects of Methyldopa on Leukocyte Subpopulations"

Douglas M. Lublin, MD, PhD
Washington University School of Medicine
"Molecular Genetic Analysis of Rh Blood Group System"

Marion Reid, PhD
New York Blood Center
"Studies on the Surface Markets of Glycophorin in Molecules in Human Red Blood Cells"

Rosetta Sue Shirey, MS, MT(ASCP)SBB
The Johns Hopkins Hospital
"An Animal Model of DSTR and DHTR"

1992

Michael P. Busch, MD, PhD
Irwin Memorial Blood Centers
"Impact of Homologous Blood Transfusion on HIV Replication and Disease in Vivo"

Loren D. Fast, PhD
Rhode Island Hospital
"Blood Transfusion and GVHD: Induction, Prevention and Modulation"

Linda L. Kelley, PhD
Vanderbilt University
"Erythropoietin Regulation of the Cell Cycle in Erythroid Progenitor Cells"

Stuart E. Lind, MD
Brigham and Women's Hospital
"Use of Conjugated Estrogens in Von Willebrand's Disease"

Joann Moulds, PhD
University of Texas Medical School
"Determination and Localization of Human Blood Group Polymorphisms on Complement Receptor One (CR1)"

Marguerite A. Neill, MD
Memorial Hospital of Rhode Island
"Use of Polymerase Chain Reaction Analysis for the Investigation of Transmission of Borrelia burgdorferi and Babesia microti by Blood Transfusion"

1991

Raymond L. Comenzo, MD
Tufts Medical Center
"On the Role of Fibronection in Peripheral Blood Progenitor Cell Amplification"

Christopher D. Hillyer, MD
Emory University Hospital Blood Bank
"Peripheral Blood Stem Cells for Allogeneic Transplantation: Development of an Animal Model-Initial Phase Investigations"

Hwai-Tai C. Lam, MS, MT(ASCP)SBB
University of California, Los Angeles
"A Cost-Effective Study of a Prospective Utilization Monitoring Program for Transfusion Practice"

Peter J. Larson, MD
University of North Carolina, Chapel Hill
"The Role of the GIA Domain in the Function of Vitamin K-dependent Coagulant Proteins"

John B. Lowe, MD
University of Michigan, Ann Arbor
"Molecular Genetics of the Human Lewis and Lewis-related Blood Group Loci"

Donald L. Siegel, PhD, MD
Hospital of the University of Pennsylvania
"Biology of Human Warm Autoimmune Hemolytic Anemia"

Priscilla Y.L. Yam, MS, FIMLS
University of California, Los Angeles
"The Detection of Minimal Residual Disease Using T-Cell Receptor Gene Rearrangements and the Polymerase Chain Reaction" 

1990

Kenneth D. Friedman, MD
University of New Mexico, Albuquerque
"Studies of von Willebrand Variants to Define the VWF Domain that Binds Glycoprotein IB"

Douglas M. Lublin, MD, PhD
Washington University
"Molecular Biological Approaches to Immunohematology: Pilot Study of Cromer Blood Group"

Allen Mayer, MD, PhD
Irwin Memorial Blood Center
"Adaptation of Capillary Separation to PCR Amplification for Donor Infectious Disease Screening"

C. Ann Rearden, MD
University of California, San Diego
"Antigenicity and Autogenicity of the MN Blood Group Sialoglycoprotein Glycophorin A"

Brian R. Smith, MD
Yale University School of Medicine
"Platelet-Leukocyte Interactions"

Douglas M. Smith, MD
University of Nebraska Medical Center
"Allogeneic Peripheral Blood Stem Cell Transplantation in Yucatan Miniature Swine"

1989

Neil Blumberg, MD
University of Rochester Medical Center
"Comparison of the Clinical and Immunologic Effects of Autologous or Homologous Blood Transfusions in Patients Undergoing Spinal Fusion Surgery"

Janice P. Dutcher, MD
Montefiore Medical Center
"Evaluation of Hematologic Changes Associated with Interlukin-2 Administration to Patients with Metastatic Malignancy and Evaluation of Migration of Activated Autologous Lymphocytes in these Patients"

Walter H. Dzik, MD
New England Deaconess Hospital
"Leukopoor Platelet Concentrates: Development and Evaluation of a Method for Preparing Leukocyte Depleted Platelet Concentrates from Single Units of Whole Blood"

Joseph P. Meyer/John A. Barrett, MD
Cook County Hospital
"Fresh Frozen Plasma Use During Massive Transfusion"

Sandra J. Nance, MS, MT(ASCP)SBB
American Red Cross, Los Angeles-Orange Counties Region
"A Comparison of the Efficiency of the Monocyte Monolayer Assay IgG Subclassing, OD450 Amniotic Fluid, and Ultrasonography in Prediction of the Severity of Hemolytic Disease of the New Born"

James A. Sloand, MD
Highland Hospital
"Characterization of Platelet Glycoprotein Ib in Chronic Renal Failure"

1988

Timothy H. Carlson, PhD
University of New Mexico, Albuquerque
"Preparation and Properties of an Improved Antithrombin III Concentrate"

Thomas S. Kickler, MD
The Johns Hopkins Hospital
"Antiallotypic Antibodies in Platelet Transfusion Recipients–Their Clinical Significance"

Joann Moulds, MS, MT(ASCP)SBB
University of Texas, Houston
"Quantitation of C4A (Rodgers) and C4B (Chido) in Order to Study Their Role in Complement Mediated Pathology"

Harry E. Prince, PhD
American Red Cross, Los Angeles-Orange Counties Region
"Lymphocyte Activation by Oxidized Erythrocytes: Characterization of the Responding Cells and the Cellular Interactions Required"

1987

Chester Andrzejewski, PhD, MD
University Intramural Correspondence
"New Assessments of Anti-Erythrocyte Autoantibody Heterogeneity in Immune Hemolytic States"

Jerome L. Gottschall, MD
The Blood Center of Southeastern Wisconsin
"Mechanism of Action of Platelet Aggregating Factor in TTP: Implications for Gamma Globulin Therapy"

Lauralynn Lebeck, MT(ASCP)SBB
St. Luke's Medical Center
"Immunoregulatory Activity of Human Bone Marrow Mononuclear Cells."

1986

John B. Lowe, MD
Howard Hughes Medical Institute
"The Molecular Biology of the Human A Blood Group Glycosyltransferases"

Paul Mintz, MD
University of Virginia Medical Center
"Correlation of Non-invasive Assessment of Platelet Morphology with Platelet Recovery and Survival"

David Scrivner, MD
American Red Cross, St. Louis Bi-State Chapter
"Hydrocortisone Impairs Lak Activity by Inhibition of Effector/Target Cell Binding"

Edward L. Snyder, MD
Yale University School of Medicine
"Calcium-Dependent Proeolysis of Actin During Storage of Platelet Concentrates"

Edward J. Victoria, PhD
University of California, San Diego
"Transmembrane Skeletal Association of the RH Antigens."

1985

James P. AuBuchon, MD
American Red Cross, Rochester Region
"Use of Indium111 as a Red Cell Label in Survival Studies"

Brooks Jackson, MD
University of Minnesota Hospitals
"Non-Detection of Human Cytomegalovirus DNA in IgM Seropositive Blood Donor Using Spot Hybridization"

Melanie S. Kennedy
Ohio State University Hospitals
"Managerial Role Delineation for Blood Bank Specialists"

Jane M. Rachel, MT(ASCP), MA
Community Blood Center of Greater Kansas City
"Evaluation of a Solid Phase Red Cell Adherence Method for Prospective Platelet Crossmatching"