Please note: AABB reserves the right to make updates to this program.
Wednesday, January 13, 2027
2:00 – 3:00 PM Eastern Time
Program Number: 27EL-702
Director/Moderator: Beth Meyer, MS, MLS(ASCP)CM, SBBCM, Supervisor, Immunohematology Reference Laboratory, American Red Cross, Maryland Heights, MO
Speaker: Margaret A. Keller, PhD, Executive, National Laboratories, American Red Cross, Philadelphia, PA; Editor-in-Chief, Immunohematology
The Rh blood group system is one of the most complex and clinically significant blood group systems in transfusion medicine. The Rh antigens D, C, E, c, and e are highly immunogenic and play a critical role in alloimmunization, transfusion compatibility, and hemolytic disease of the fetus and newborn (HDFN). Molecular variation within the RHD and RHCE genes contributes to weak and partial antigen expression, loss of high prevalence antigens and gain of low prevalence antigens, all of which can complicate serologic testing and clinical interpretation. Understanding Rh antigen diversity and the molecular methods that predict complex Rh phenotypes are critical to assessing risk of alloimmunization, resolving typing discrepancies, and guiding transfusion and prenatal management.
This eCast will explore the molecular basis of Rh antigen expression with a focus on D, C, E, c, and e, and correlate these findings with serologic results. Practical applications in the transfusion service and reference laboratory settings, including strategies for resolving complex cases and optimizing patient care, will be reviewed. Because the management of patients with complex Rh phenotypes often requires collaboration between the blood bank and the patient care team, this activity is interprofessional in nature. Through a shared understanding of Rh complexity, healthcare professionals will be better equipped to collaborate in the prevention of alloimmunization, selection of compatible blood products, and management of patients at risk for HDFN.
After participating in this educational activity, participants should be able to:
Registration includes access to both the live and on-demand version of this eCast.
If you are a facility interested in participating in this eCast, simply complete the Group Viewing registration form and AABB will provide detailed instructions to share with your team approximately one week prior to the live program (each team member to register for the program utilizing a promocode). For single viewers, simply click on the Register button below to register.
Please note: registration for the live eCast will close 1 hour prior to the eCast start time. If you register after this time, you will receive access to the on-demand eCast when it is available.
| Single Viewer | Register |
| Group Viewing | Register |
This activity is eligible for one (1.0) continuing education credit/contact hour for Physicians, California Nurses, California Lab Personnel, Florida Lab Personnel and General Participation credit. AABB reserves the right to reduce or increase the number of credits granted based on the final activity duration. For more information on each credit type please visit our Continuing Education Credits webpage.
There is no financial support for this activity.
In support of improving patient care, this activity has been planned and implemented by the Association for the Advancement of Blood & Biotherapies (AABB), which is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Physicians (ACCME): AABB designates this live activity for a maximum of one (1.0) AMA PRA Category 1 CreditTM. AABB designates this enduring activity for a maximum of one (1.0) AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Claiming Credit
Live Activity - Upon completion of the live activity, you will receive instructions to complete your evaluation, which is necessary to claim credit and receive your certificate of attendance/completion (credit must be claimed by the date provided in the instructions). The evaluation can be found by logging into the AABB Education Platform.
Enduring Activity - Once the enduring (on-demand) program is available, you will receive instructions to access the AABB Education Platform. Upon completion of viewing the enduring activity, you will need to complete the evaluation, which is necessary to claim credit and receive your certificate of completion (credit must be claimed by the date provided in the AABB Education Platform).
Program & Credit Expiration Dates:
Disclosure Declaration
It is the policy of the Association for the Advancement of Blood & Biotherapies to ensure independence, balance, objectivity, and scientific rigor and integrity in all of its CE activities. Faculty must disclose to the participants any relationships with commercial companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. AABB has evaluated, identified, and mitigated any potential conflicts of interest through a rigorous content validation procedure, use of evidence-based data/research, and a multidisciplinary peer review process. The following information is for participant information only. It is not assumed that the presence of such relationships will have a negative impact on the presentations.
Disclosures for the planners of this event can be found here. Disclosures for the program faculty, peer reviewers, and AABB personnel are provided at the beginning of the program.
Beth Meyer, MS, MLS(ASCP)CM SBBCM is a supervisor in the Immunohematology Reference Laboratory for The American Red Cross in Maryland Heights, MO. She completed her undergraduate education at Missouri Western State University in 2009 and received her Master of Science in Clinical Laboratory Science from University of Massachusetts – Lowell in 2013. She spent several years as a generalist MLS before developing an interest in blood banking. She joined The American Red Cross in 2015 as an IRL Technologist where she was involved in training new staff members before moving into management. She completed the Specialist in Blood Banking and Transfusion Medicine Program from The American Red Cross and became SBB certified in 2023.
Margaret A. Keller, PhD is the Executive of National Laboratories at the American Red Cross. She is senior director of the American Rare Donor Program (ARDP) with more than 130,000 registered rare donors. Margaret received her PhD in molecular genetics from the University of Pennsylvania. She is ARDP liaison to the Molecular Testing Standards Unit of the AABB, chair of the ISBT Working Party on Red Cell Immunogenetics and Blood Group Terminology and member of the ISBT Working Party on Rare Donors. She is adjunct Associate Professor at Thomas Jefferson University and is editor-in-chief of the journal Immunohematology. She is recipient of multiple awards including the Sally Frank Memorial Award from AABB.
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