AABB, with the valued assistance of its expert member committees, develops a variety of resources to help guide professionals in keeping abreast of clinical issues in transfusion medicine. AABB is a leader in producing clinical practice guidelines for utilization of blood components. In addition, the association develops informational documents and guidance regarding a wide range of clinical and technical topics facing transfusion medicine providers.
Published in the Annals of Internal Medicine, these guidelines reflect the most up-to-date published evidence available, and replace the interim recommendations from early 2021. The AABB Board of Directors commissioned a committee of experts to draft clinical practice guidelines. Consistent with previous clinical practice guidelines from AABB, the committee performed a formal systematic review and meta-analysis of the data and used GRADE methodology to formulate the current recommendations. The committee focused exclusively on randomized clinical trial data to minimize the risk of bias.
Updated to reflect the most up-to-date published evidence available, these guidelines provide pragmatic advice to assist clinicians in making decisions about the use of red blood cell transfusions. Published online in October 2016 in the “Journal of the American Medical Association,” the guidelines recommend the use of more restrictive hemoglobin thresholds for transfusion and standard-issue rather than “fresh” RBCs.