AABB Foundation Recognizes Shang-Chuen Wu as 2026 Scholar

The AABB Foundation has named Shang-Chuen Wu, PhD, instructor in pathology at Brigham and Women’s Hospital and Harvard Medical School, a 2026 AABB Foundation Scholar.

Wu earned this distinction following completion of his AABB Foundation-funded research investigating the immunological mechanisms underlying naturally occurring anti-ABO(H) antibody formation. These antibodies remain the most common immunological barrier to transfusion and transplantation.

His work established a novel preclinical model demonstrating how blood group-positive microbes and innate immune lectins shape anti-ABO(H) antibody responses and influence individual risk for transfusion complications.

“The AABB Foundation supported project led to a novel preclinical model to study anti-ABO(H) antibody formation and specificity,” Wu said. “Our findings suggest that blood group-positive microbes and innate immune lectins can shape anti-ABO(H) antibody responses, clarifying individual risk for transfusion complications and informing strategies to improve transfusion safety.”

Wu’s research lies at the intersection of glycobiology, microbiology, immunology and transfusion medicine, with a long-term goal of developing mechanism-based strategies to reduce immunological risk and improve transfusion and transplantation safety.

The AABB Foundation will honor Wu at the 2026 AABB Annual Meeting for his scientific contributions.