Low Yield Platelets: Impact To Platelet Availability and How To Implement In Your Hospital (24EL-404)

Please note: AABB reserves the right to make updates to this program.

Wednesday, January 31, 2024 - On-Demand Available
Program Number: 24EL-404

  • Educational Track: Technical/Clinical
  • Topics: Blood Donation & Collection, Patient Transfusion
  • Intended Audience: Directors, Hospital Blood Banks, Hospitals, Laboratory Staff, Managers/Supervisors, Medical Directors, Physicians, Residents/Fellows, Students (MD, MT, SBB), Technologists, Transfusion Safety Officers
  • Teaching Level: Advanced, Basic, Intermediate
  • Director/Moderator: Elizabeth P. Crowe, MD, PhD, Assistant Professor, Department of Pathology, Division of Transfusion Medicine, Johns Hopkins University School of Medicine; Medical Director, Blood Bank, Johns Hopkins Hospital, Baltimore, MD

    • Baia Lasky, MD, Divisional Chief Medical Officer, Medical Director, Georgia and Alabama/Mississippi Regions, American Red Cross Biomedical Services, Douglasville, GA
    • Wen Lu, MD, Medical Director, Center for Regenerative Biotherapeutics, Transfusion Medicine Consultant, Mayo Clinic, Rochester, MN
  • Program Description

    Apheresis-derived platelet units containing fewer platelets than the Food and Drug Administration (FDA)-required minimum (3.0 X10^11 platelets per unit) are labelled as "low-yield platelets." Given that platelet inventory shortages continue to be an ongoing challenge, implementation of low-yield platelets may increase the available platelet inventory and improve patient care; however, knowledge gaps persist with regard to the safety and efficacy of low yield platelets.

    This lecture-format program will discuss the rationale and available evidence for low-yield platelets from the perspectives of a blood collection center and a hospital transfusion service. Further research is needed to better understand the benefits and limitations of low-yield platelets and optimize transfusion strategies in different patient populations.

    Learning Objectives

    After participating in this educational activity, participants should be able to:

    • Describe the concept of low-yield platelets and their significance in the blood supply chain.
    • Analyze the available evidence for safety and effectiveness of low-yield platelet transfusions.
    • Discuss strategies for effective implementation of low-yield platelets including patient selection criteria, inventory management, and tracking of transfusion outcomes.


    Please note: if you registered for the live eCast you do not need to register for the on-demand eCast (access to the on-demand eCast was included with the live eCast registration).

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    Continuing Education Credit

    This activity is eligible for one (1) continuing education credit/contact hour for Physicians, Nurses (including California-based nursing professionals through CBRN), California Lab Personnel, Florida Lab Personnel and General Participation credit. AABB reserves the right to reduce or increase the number of credits granted based on the final activity duration. For more information on each credit type please visit our Continuing Education Credits webpage.

    There is no financial support for this activity.

    Jointly Accredited Provider

    In support of improving patient care, this activity has been planned and implemented by the Association for the Advancement of Blood & Biotherapies (AABB) and CME Outfitters, LLC. CME Outfitters LLC. is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

    Physicians (ACCME): CME Outfitters, LLC, designates this live activity for a maximum of one (1) AMA PRA Category 1 CreditTM. CME Outfitters, LLC, designates this enduring activity for a maximum of one (1) AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Claiming Credit
    Live Activity - Upon completion of the live activity, you will receive instructions to complete your evaluation, which is necessary to claim credit and receive your certificate of attendance/completion (credit must be claimed by the date provided in the instructions). The evaluation can be found by logging into the AABB Education Platform.

    Enduring Activity - Once the enduring (on-demand) program is available, you will receive instructions to access the AABB Education Platform. Upon completion of viewing the enduring activity, you will need to complete the evaluation, which is necessary to claim credit and receive your certificate of completion (credit must be claimed by the date provided in the AABB Education Platform).

    Program & Credit Expiration Dates:

    • Live Activity Program Date: January 31, 2024; Credit Expiration Date: February 29, 2024
    • Enduring Activity Program Dates: January 31, 2024 – January 30, 2027; Credit Expiration Date: January 30, 2027

    Disclosure Declaration

    It is the policy of CME Outfitters, LLC, and the Association for the Advancement of Blood & Biotherapies to ensure independence, balance, objectivity, and scientific rigor and integrity in all of their CE activities. Faculty must disclose to the participants any relationships with commercial companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. CME Outfitters, LLC, has evaluated, identified, and mitigated any potential conflicts of interest through a rigorous content validation procedure, use of evidence-based data/research, and a multidisciplinary peer review process. The following information is for participant information only. It is not assumed that the presence of such relationships will have a negative impact on the presentations.

    Disclosures for the planners of this event can be found here. Disclosures for the program faculty, peer reviewers, and CME Outfitters, LLC. personnel are provided at the beginning of the program.

    Faculty Biographies

    Dr. Elizabeth (Liz) Crowe is an Assistant Professor in the Department of Pathology at the Johns Hopkins University School of Medicine. She is also the Medical Director of the blood bank at the Johns Hopkins Hospital. Dr. Crowe completed her M.D. and Ph.D. in Molecular Cell Biology and Genetics at Drexel University College of Medicine. She completed her residency training in Anatomic and Clinical Pathology at Weill Cornell Medicine and New York Presbyterian Hospital, followed by a fellowship in Transfusion Medicine at Johns Hopkins. Her areas of interest include transfusion medicine education, patient blood management, and immunohematology. She also serves as the Medical Director of the Specialist in Blood Bank Technology/Transfusion Medicine (SBBT/TM) program at Johns Hopkins. She is a member of AABB and recently joined the eLearning Committee.

    Dr. Baia LaskyDr. Baia Lasky is board-certified in Blood Banking and Transfusion Medicine. She received her training at UCLA and joined the team of medical directors at the American Red Cross in 2019. She is currently a Divisional Chief Medical Officer and provides medical leadership for key organizational initiatives including inventory stewardship, platelet transfusion practices, and donor safety and education.

    Wen Lu, MDWen Lu, MD, is the medical director of the Center for Regenerative Biotherapeutics and Transfusion Medicine Consultant at the Mayo Clinic. Previously, she was medical director of the Kraft Family Blood Donor Center, associate medical director of the transfusion service at Brigham and Women’s Hospital, and program director of the Harvard Medical School fellowship in transfusion medicine. Lu received her bachelor of science degree in biochemistry from the University of Washington and earned her medical degree at New York Medical College. She continued her training at the Hospital of University of Pennsylvania as a clinical pathology resident and transfusion medicine fellow. Her scholarly interests in transfusion medicine include perinatal immunohematology, hospital inventory management, transfusion safety and hemovigilance. Lu is a member of the podcast committee for the journal Transfusion. She has been active in AABB and served as a member of the Circular of Information Task Force, team lead of the Annual Meeting Education Committee (AMEC), Transfusion Medicine Subsection Coordinating Committee (TMSCC) liaison to the Hemovigilance Committee, and chair of the AABB Clinical Hemotherapy Subsection within the TMSCC. As subsection chair, she helped update the AABB Guide for Prenatal and Perinatal Immunohematology and was editor of the AABB Guide to Antibody Identification and the AABB Guide to the Laboratory Evaluation of Transfusion Reactions.